research Low temperature abolishes human cellular circadian rhythm through Hopf bifurcation
Cold temperatures can stop human cell circadian rhythms, but warming restores them.
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research Illuminating microflora: shedding light on the potential of blue light to modulate the cutaneous microbiome
Blue light might help treat skin conditions by affecting the skin's bacteria.
research Reproductive dysfunction in women with epilepsy: recommendations for evaluation and management
Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.
research Clinical Pharmacokinetics and Pharmacodynamics of Finasteride
Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
research Optimal Management of Hair Loss (Alopecia) in Children
Effective management of children's hair loss involves accurate diagnosis, various treatments, and supportive care.
research Update on the dermatologic use of systemic glucocorticosteroids
Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.
research Effectiveness of the Mentha spicata leaves in reducing testosterone levels and aggressive behaviour in female Wistar albino rats treated with testosterone propionate
Mentha spicata leaves lower testosterone and aggression in female rats.
research Generation of Genetically Modified Rats Using CRISPR/Cas9 Genome-Editing System to Reveal Novel Vitamin D Actions
Genetically modified rats help reveal how vitamin D affects bone and skin health.
research Retinoids
Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.
research Optimization of photobiomodulation therapy for spinal cord injury: A review
Standardizing light therapy methods could improve spinal cord injury treatment.
research Gene Array Profiling and Immunomodulation Studies Define a Cell-Mediated Immune Response Underlying the Pathogenesis of Alopecia Areata in a Mouse Model and Humans
Alopecia areata is caused by an immune response, and targeting immune cells might help treat it.
research Dihydrotestosterone and Finasteride Effects on Alcohol Cue‐Elicited Brain Activity in Males With Heavy Episodic Drinking
Finasteride may help reduce alcohol cravings and related brain activity.
research Endogenous neurosteroids modulate epileptogenesis in a model of temporal lobe epilepsy
Neurosteroids may help prevent seizures in epilepsy.
research Does maternal exposure to artificial food coloring additives increase oxidative stress in the skin of rats?
Maternal exposure to artificial food coloring may increase skin disease risk in rat offspring.
research ANDROGENETIC ALOPECIA
Minoxidil was promising for treating male and female pattern baldness in 1994, but more research on genetics and other treatments was needed.
research Glia-derived steroids modulate epileptogenesis in a model of temporal lobe epilepsy
Neurosteroids from glia cells help control seizure development in epilepsy.
research The significance of CYP11A1 expression in skin physiology and pathology
CYP11A1 is crucial for skin health and disease by producing important steroids.
research Steroidogenic enzymes in skin.
Finasteride helps hair growth by reducing DHT levels.
research Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands
Mice without certain skin enzymes have faster hair growth and bigger eye glands.
research Spironolactone Therapy for Hirsutism in a Hyperandrogenic Woman
Spironolactone may help reduce excessive hair growth in women with high male hormone levels.
research Cytoprotectivity of the natural honey against the toxic effects of Doxorubicin in mice
Natural honey protects against Doxorubicin's harmful effects.
research In vitro biotransformation of finasteride in rat hepatic microsomes. Isolation and characterization of metabolites.
research Alleviation of Mechanical Allodynia by 14,15-Epoxyeicosatrienoic Acid in a Central Poststroke Pain Model: Possible Role of Allopregnanolone and δ-Subunit-Containing Gamma-Aminobutyric Acid A Receptors
14,15-EET may help reduce poststroke pain by affecting certain brain proteins.
research Allopregnanolone-mediated protective effects of progesterone on tributyltin-induced neuronal injury in rat hippocampal slices
Progesterone protects neurons from damage by converting to allopregnanolone, which works through GABAA receptors.
research Guidelines on the use of finasteride in androgenetic alopecia
Taking 1 mg of finasteride daily can increase hair count and improve hair appearance, but it may have side effects on sexual function and a potential risk of prostate cancer. It may not be effective for postmenopausal women unless taken in higher doses.
research The effect of topical minoxidil treatment on follicular sulfotransferase enzymatic activity.
Topical minoxidil does not change the activity of hair follicle enzymes that metabolize it.
research Drug interactions between common dermatological medications and the oral anti-COVID-19 agents nirmatrelvir-ritonavir and molnupiravir
Some skin medications can have harmful interactions with the COVID-19 drug nirmatrelvir-ritonavir, but not with molnupiravir.
research Racial and Ethnic Disparities in Persistent Chemotherapy-Induced Alopecia Among Women With Breast Cancer
Asian women with breast cancer experience the highest rates of long-term hair loss and related distress after chemotherapy.
research Vitamin D and the Parenteral Nutrition Patient
Vitamin D is crucial for bone health and preventing serious diseases.
research General adverse response to cyclophosphamide in Chinese patients with systemic autoimmune diseases in recent decade — a single-center retrospective study
Cyclophosphamide often causes gastrointestinal issues, hair loss, and low blood cell counts in Chinese patients with autoimmune diseases.