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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

A chimeric keratin partially improved skin structure in mice lacking keratin 5, but didn't fully restore normal skin.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

CREB, a protein that can promote cancer traits, is controlled by β-catenin in skin cancer cells.

A man developed autoimmune issues after a transplant, improved with treatment, but died from leukemia relapse.

Certain substances can protect against ear damage from some antibiotics in zebrafish.

Genetic screening can help diagnose and manage infertility in Slovenian couples.

Disrupted citric acid metabolism stops hair growth.

A 9-year-old girl with a healthy immune system was successfully treated for a severe fungal scalp infection caused by Microsporum audouinii.

The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.

Women with PCOS may have a reduced ability to fight breast tumor cells over time.

CAR-T cell therapy shows promise for treating autoimmune disorders but faces challenges like complex manufacturing and limited tissue penetration.

Loss of Pten in certain hair follicle stem cells increases skin cancer risk.

Two patients with Cronkhite-Canada syndrome achieved remission after treatment.

The document concludes that careful diagnosis is crucial for chromosome 13q deletion syndrome, tamoxifen can cause reversible eye damage, finasteride may be linked to cataracts, and OCT is useful for diagnosing macular diseases.

T-cell reconstitution after thymus transplantation can cause hair whitening and loss.

Iron is essential for many body functions, and its deficiency causes serious health problems.

Early intervention is crucial for managing blood clotting issues in pregnant women with COVID-19.

Cyproterone acetate is a safe treatment that causes mild feminizing effects in adolescent trans-girls.

Telitacicept effectively improved hair regrowth in a woman with lupus and alopecia.

A new genetic mutation was found causing hair and eye issues in a boy.

A cystic fibrosis patient developed Cushing's syndrome from a drug interaction between itraconazole and budesonide, which improved after stopping the medications.

Autoimmune gastritis is a common cause of iron deficiency and should be included in diagnostic guidelines.

Vitamin C deficiency changes gene expression, affecting skin and hair health.

Activated protein C helps protect mice from long-term radiation damage.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

Nanotechnology improves CRISPR-Cas9 delivery for cancer treatment, but challenges remain.

Down Syndrome patients with Alopecia Areata often have hypothyroidism and specific immune abnormalities.

Protein Kinase Cε increases skin sensitivity to UV damage and skin cancer risk.