122 citations
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April 2020 in “American Journal Of Pathology” Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
22 citations
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March 2023 in “Bioengineering” Stem cell therapies may help improve symptoms and quality of life for people with epidermolysis bullosa.
19 citations
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August 2024 in “Journal of Translational Medicine” Epidermal stem cells are vital for skin healing and have potential for treating skin disorders.
50 citations
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February 2016 in “Journal of Investigative Dermatology” A mutation in the KRT25 gene causes a rare hair disorder with thin, woolly hair.
39 citations
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September 2007 in “BMC developmental biology” Neuregulin3 affects cell development in the skin and mammary glands.
9 citations
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November 2024 in “Journal of Wound Management Official journal of the European Wound Management Association” Cold Plasma shows promise for healing wounds by killing bacteria and helping tissue grow.
2 citations
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December 2023 in “Advanced science” Glycosaminoglycans help heal wounds but aren't yet ready for clinical use.
1 citations
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December 2023 in “Life” PRP helps skin heal, possibly through special cells called telocytes.
January 2026 in “International Journal of Molecular Sciences” S100a4 is key for hair growth in cashmere goats.
908 citations
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July 2015 in “British Journal of Dermatology” Acute wounds heal well, but chronic wounds struggle due to ongoing inflammation and poor tissue repair.
854 citations
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February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
561 citations
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April 2003 in “Journal of Investigative Dermatology” CD34 is a marker for isolating stem-like cells in mouse hair follicles.
426 citations
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August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
266 citations
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January 2016 in “Development” YAP and TAZ are crucial for skin cell growth and repair.
129 citations
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July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
114 citations
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February 2023 in “International Journal of Molecular Sciences” The skin microbiome is crucial for skin health, and more research is needed to explore its role and potential treatments.
105 citations
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December 2017 in “Journal of Biological Engineering” Artificial skin grafts face immune rejection, but stem cells may improve future designs.
100 citations
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November 2017 in “EMBO Reports” Metabolic signals and cell shape influence how cells develop and change.
98 citations
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December 2015 in “The Journal of Cell Biology” Keratin is crucial for skin barrier formation and affects mitochondrial function.
97 citations
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December 2021 in “Cells” Designing effective fluorescence microscopy experiments requires careful consideration of hardware, biological models, and imaging agents.
97 citations
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May 2019 in “Frontiers in Cell and Developmental Biology” Abnormal ECM and immune cell interactions can cause skin diseases.
87 citations
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March 2015 in “The EMBO Journal” Adult tissue stem cells can adapt and switch roles to help repair and maintain the body.
79 citations
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August 1998 in “The Journal of Cell Biology” Keratin 16 delays skin maturation and affects skin and hair development in mice.
73 citations
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January 2002 in “Journal of Investigative Dermatology” Epidermal stem cells don't use gap junctions to communicate.
54 citations
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May 2021 in “International Journal of Molecular Sciences” Advances in mechanobiology and immunology could lead to scarless wound healing.
47 citations
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April 2021 in “BMC Medical Genomics” Certain gene variants can influence acne risk and severity.
46 citations
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September 2023 in “Cell Reports” Sebaceous glands can regenerate after injury using stem cells from hair follicles.
44 citations
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February 2023 in “Cell” Fingerprints form uniquely before birth due to specific genetic pathways and local signals.
40 citations
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August 2021 in “International Journal of Molecular Sciences” The subcutaneous fascia is key to fast wound healing and could improve treatments for chronic wounds and scarring.
39 citations
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November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Fatp4 is crucial for healthy skin development and function.