56 citations
,
June 2015 in “Nature Protocols” Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.
2 citations
,
January 2020 in “BioMed Research International” Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.
2 citations
,
October 2015 in “Indian journal of science and technology” SM-215 promotes hair growth by improving the environment around hair follicles.
November 2025 in “EXPERIMENTAL ANIMALS” Stingless bee propolis may help regenerate hair follicles and improve pigment function in chemotherapy-induced hair loss.
April 2024 in “Frontiers in physiology” Immune cells are crucial for hair growth and preventing hair loss.
April 2017 in “Journal of Investigative Dermatology” Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.
146 citations
,
May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.
98 citations
,
July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
76 citations
,
August 2018 in “International Journal of Cosmetic Science” Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
30 citations
,
October 2016 in “Current research in translational medicine” Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.
12 citations
,
July 2014 in “Journal of Investigative Dermatology” Chemotherapy causes complex changes in hair follicle cells that can lead to hair loss.
5 citations
,
October 2024 in “International Journal of Biological Sciences” A peptide from hair follicle stem cells can boost hair growth.
5 citations
,
February 2022 in “Frontiers in physiology” Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.
2 citations
,
January 2020 in “American Journal of Clinical Research and Reviews” All skin diseases might start in hair follicles.
May 2026 in “Frontiers in Cell and Developmental Biology” Hair follicle organoids can help study hair biology and disorders but need improvements for wider use.
January 2026 in “Avicenna Bulletin” Aligning hair implants with natural growth patterns improves hair transplant results.
Researchers developed a new device that improves non-incision hair transplant efficiency.
835 citations
,
October 2008 in “Nature Genetics” Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
240 citations
,
April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
192 citations
,
March 2017 in “Cell host & microbe” Hair follicle development and microbes help regulatory T cells gather in newborn skin.
175 citations
,
December 2014 in “PLoS Biology” Macrophages help activate hair follicle stem cells, affecting hair growth and skin repair.
159 citations
,
December 2007 in “American Journal of Pathology” Stress-related substance P may lead to hair loss and negatively affect hair growth.
149 citations
,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.
136 citations
,
May 2019 in “Cells” Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
122 citations
,
July 2005 in “The FASEB journal” Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
113 citations
,
November 2017 in “Scientific Reports” Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
109 citations
,
October 2007 in “Journal of pineal research” Melatonin helps regulate hair growth and protects the hair follicle from stress.
106 citations
,
March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
100 citations
,
November 1996 in “Molecular Medicine Today” Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.
98 citations
,
February 2007 in “Seminars in Cell & Developmental Biology” Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.