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Growth Factors IGF-1 and KGF and Adipose-Derived Stem Cells Promote Migration and Viability of Primary Human Keratinocytes in an In Vitro Wound Model

research Growth factors IGF-1 and KGF and adipose-derived stem cells promote migration and viability of primary human keratinocytes in an in vitro wound model

8 citations , February 2025 in “Frontiers in Medicine”

IGF-1, KGF, and stem cells help skin cells move and survive, potentially speeding up wound healing.

research Melanocytes from the outer root sheath of human hair and epidermal melanocytes display improved melanotic features in the niche provided by cGEL, oligomer-cross-linked gelatin-based hydrogel

7 citations , July 2016 in “Journal of Biomedical Materials Research Part A”

cGEL hydrogel improves melanin production in skin cells, making it a promising option for skin treatments.

research Single-stage transplantation combined with epidermal stem cells promotes the survival of tissue-engineered skin by inducing early angiogenesis

11 citations , March 2023 in “Stem Cell Research & Therapy”

Epidermal stem cells improve skin graft survival by promoting early blood vessel formation.

research Fabrication and characterization of epithelial scaffolds for hair follicle regeneration

4 citations , May 2012 in “Tissue Engineering and Regenerative Medicine”

Scientists created three types of structures to help regrow hair follicles, and all showed promising results for hair regeneration.

research Effect of Cultured Dermal Substitute Composed of Collagen Sponge Seeded with Fibroblasts in Simultaneous Skin Graft Overlay

1 citations , March 2001 in “JOURNAL OF THE KYORIN MEDICAL SOCIETY”

Fibroblast-seeded collagen sponges help skin regrowth but don't improve graft survival.

research Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures

November 2023 in “npj regenerative medicine”

Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.

research An improved and rapid method to construct skin equivalents from human hair follicles and fibroblasts

48 citations , August 2001 in “Experimental dermatology”

Researchers created a quick, cost-effective way to make skin-like tissue from hair follicles and fibroblasts.

research A Human Hair Keratin Hydrogel Scaffold Enhances Median Nerve Regeneration in Nonhuman Primates: An Electrophysiological and Histological Study

69 citations , October 2013 in “Tissue Engineering Part A”

Keratin hydrogel improves nerve regeneration and motor recovery.

research Cultivation of Murine Hair Follicles as Organoids in a Collagen Matrix

87 citations , October 1987 in “Journal of Investigative Dermatology”

One-Step Generation of Core–Shell Biomimetic Microspheres Encapsulating Double-Layer Cells Using Microfluidics for Hair Regeneration

research One-step generation of core–shell biomimetic microspheres encapsulating double-layer cells using microfluidics for hair regeneration

7 citations , January 2023 in “Biofabrication”

A new method efficiently creates cell spheres that help regenerate hair.

research Degradation of human hair keratin scaffold implanted for repairing injured skeletal muscles.

5 citations , October 2002 in “PubMed”

Human hair keratin scaffolds help repair injured muscles by breaking down and activating muscle cell growth.

research Aligned membranes regulate wound healing via MMP12 secreted by macrophages

January 2025 in “PLoS ONE”

Aligned membranes improve wound healing by reducing scars and promoting skin regeneration.

research A Novel Crosslinking Approach for Biomanufacturing of a Collagen‐Based Skin Dermal Template

December 2024 in “Macromolecular Bioscience”

The new collagen template speeds up production and supports skin healing without harmful reactions.

research Matrigel uses in cell biology and for the identification of thymosin β4, a mediator of tissue regeneration

15 citations , September 2018 in “Applied Biological Chemistry”

Matrigel supports cell growth and repair, and thymosin beta 4 aids tissue regeneration and healing.

research In vitro 3D organotypic hair follicle-model for high-throughput substance testing

September 2016 in “Toxicology letters”

The 5050 MHA42MCS45 hydrogel blend is suitable for repairing load-bearing soft tissues.

Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Tissue Regeneration

research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration

August 2015 in “MOJ proteomics & bioinformatics”

ePUKs could be valuable for regenerative medicine due to their wound healing abilities.

research 312 CRISPR/Cas9-based targeted genome editing for correction of recessive dystrophic epidermolysis bullosa using iPS cells

1 citations , September 2019 in “Journal of Investigative Dermatology”

The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.

research INNOVATIVE THERAPIES IN REGENERATIVE MEDICINE AND TRANSPLANTATION

January 2024 in “Wiadomości Lekarskie”

DEC cells show promise as a safe and effective treatment for Duchenne muscular dystrophy.

research Restructuring skin equivalents with human hair follicle orscs and fibroblasts

March 2007 in “Journal of Plastic Reconstructive & Aesthetic Surgery”

A new method was developed to create better skin models for healing and reconstruction.

research 626 Early-stage bilayer tissue-engineered skin substitute formed by adult skin progenitor cells produces an improved skin structure in vivo

April 2021 in “Journal of Investigative Dermatology”

Early-stage skin substitutes improve wound healing and skin structure.

Three-Dimensional Cultured Human Dermal Papilla Cells in HGC-Coated Environments Enhance Hair Regeneration and Artificial Skin Integration

research Three-Dimensional Cultured Human Dermal Papilla Cells in HGC-Coated Environments Enhance Hair Regeneration and Artificial Skin Integration

January 2024 in “Biomaterials Research”

3D-cultured cells in HGC-coated environments improve hair growth and skin integration.

Mesenchymal Stem Cells Paracrine Proteins From Three-Dimensional Dynamic Culture System Promoted Wound Healing in Third-Degree Burn Models

research Mesenchymal stem cells paracrine proteins from three‐dimensional dynamic culture system promoted wound healing in third‐degree burn models

July 2023 in “Bioengineering & translational medicine”

Mesenchymal stem cell proteins in a special gel improved healing of severe burns.

research Human Wharton's Jelly Stem Cells and Its Conditioned Medium Enhance Healing of Excisional and Diabetic Wounds

84 citations , August 2013 in “Journal of Cellular Biochemistry”

Human Wharton's jelly stem cells improve wound healing.

research Wound-healing effects of frozen-thawed allogeneic fibroblast sheet transplantation and xenogeneic fibroblast cell sheet transplantation cultured on a new substrate

March 2025 in “Tissue and Cell”

Frozen-thawed fibroblast sheets enhance wound healing and hair growth in mice.

research The Simplest Protocol for Rapid and Long-Term Culture of Primary Epidermal Keratinocytes from Human and Mouse

2 citations , January 2019 in “Methods in molecular biology”

A new method helps grow skin cells from humans and mice more easily and quickly.

research Architecture of Reconstructed Epidermis on Collagen Lattices Varies according to the Method Used: A Comparative Study

9 citations , January 1990 in “Skin Pharmacology and Physiology”

The method and source of keratinocytes affect the structure of reconstructed skin.

research Mesenchymal Stem Cells From Mouse Hair Follicles Reduce Hypertrophic Scarring in a Murine Wound Healing Model

13 citations , January 2022 in “Stem cell reviews and reports”

Mouse stem cells from hair follicles can improve wound healing and reduce scarring.

research Current application of tissue-engineered dermal scaffolds mimicking the extracellular matrix microenvironment in wound healing

11 citations , January 2025 in “Regenerative Therapy”

Tissue-engineered scaffolds help heal difficult wounds by supporting cell growth and repair.

Corneal Endothelial Cell Fate Is Maintained by LGR5 Through the Regulation of Hedgehog and Wnt Pathways

research Corneal Endothelial Cell Fate Is Maintained by LGR5 Through the Regulation of Hedgehog and Wnt Pathway

73 citations , April 2013 in “Stem cells”

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

research In Vitro Culture Methods of Skin Cells for Optimal Skin Reconstruction by Tissue Engineering

2 citations , August 2011 in “InTech eBooks”

New methods for growing skin cells can improve skin grafts by building blood vessels within them.

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