September 2018 in “Value in Health” Orphan drug benefit scores in Germany are influenced by phase III data and lack of alternatives, but not linked to price or discounts.
October 2008 in “Australasian Journal of Dermatology” Medical practitioners need to understand basic statistics to properly evaluate clinical trials and avoid unethical designs.
Type XVII collagen helps control skin cell growth and may have anti-aging effects.
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January 2018 Sphingosine 1-phosphate and its receptor S1PR3 are key in controlling mechanical pain.
Keratinocytes can reverse the effects of the GNAQ oncogene, inhibiting melanoma cell growth.
July 2023 in “Developmental medicine and child neurology/Developmental medicine & child neurology” DFMO treatment improves hair growth, muscle tone, and development in Bachmann-Bupp syndrome patients.
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September 2003 in “Clinical endocrinology” Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.
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October 2025 in “Colorectal Disease” Early-onset colorectal cancer requires better physician awareness, risk-based screening, and stigma reduction to improve patient experiences.
March 2026 in “Immunological Medicine” Janus kinase inhibitors help some people with severe alopecia areata regrow hair, but not everyone responds, and relapses can happen.
August 2025 in “International Journal of Women’s Dermatology” Stopping and restarting JAK inhibitors during pregnancy in women with alopecia areata leads to hair loss and regrowth, with most pregnancies resulting in healthy babies.
October 2022 in “Biomedicines” Finasteride in male rats causes liver and metabolic issues in their offspring.
January 2026 in “Pediatrics International” Live vaccines can be safely given to infants with a FOXN1 variant if their immune function improves over time.
ILC1-like cells may contribute to hair loss in alopecia areata and could be new treatment targets.
A man wrongly believed he had parasites, showing that delusional infestation can affect men and is often linked with other psychiatric issues, but can be treated with antipsychotics.
Lhx2 helps retinal cells respond to signals for eye development.
Hairless mammals evolved quickly in both gene and non-gene areas related to skin and hair.
CCC1 is essential for ion balance and proper plant cell function.
Different types of sun exposure can damage skin cells and affect healing, with chronic exposure being more harmful, and certain immune cells help in the repair process.
Hair can naturally regain color, and stress might influence greying and its reversal.
Moles may stop growing due to cell cooperation, not just because of individual cell aging.
Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.
IL-18 signaling helps mature Tregs move into the thymus.
Skin cells can naturally limit the growth of cancerous changes by balancing cell renewal and differentiation.