21 citations
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January 2023 in “Biomaterials Science” Microneedle patches with alpha-arbutin and resveratrol can effectively reduce skin pigmentation without irritation.
January 2023 in “Indian Dermatology Online Journal” Micropigmentation is a cosmetic tattooing technique for hiding skin issues and creating permanent makeup, but it can have side effects.
June 2025 in “Australasian Journal of Dermatology” Pigmented rings with central clearing help diagnose melasma more accurately.
9 citations
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September 2020 in “Journal of cosmetic dermatology” A woman developed vitiligo from repeated eyebrow microblading.
September 2023 in “Journal of the American Academy of Dermatology” Patients often overestimate their skin type, affecting sun protection and treatment plans.
3 citations
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August 2017 in “Clinical case reports” A rare skin condition causes red and dark patches on the face and limbs.
3 citations
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January 2023 in “Journal of Cutaneous and Aesthetic Surgery” Intradermal PRP significantly improved melasma in dark skin, with lasting results and no relapse after 3 months.
1 citations
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July 2015 in “British Journal of Dermatology” Imiquimod improved skin pigmentation in most patients with xeroderma pigmentosum and may prevent further skin cancer, but some treatments can have side effects.
March 2026 in “Portuguese Journal of Dermatology and Venereology” Avoid hair dye after microneedling to prevent scalp pigmentation.
9 citations
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May 2005 in “Facial plastic surgery” Laser hair removal can be safe and effective for dark-skinned individuals with the right laser settings.
January 2009 in “Elsevier eBooks” 25 citations
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October 1985 in “Archives of Ophthalmology” The pigment in black eyeliner can spread in the skin and may cause permanent eyelash loss.
84 citations
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April 2005 in “Dermatologic Clinics” Treatments for melanin disorders exist, but more effective options needed.
November 2024 in “Karnataka Pediatric Journal”
11 citations
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April 2013 in “SpringerPlus” Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.
3 citations
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October 1996 in “International Journal of Dermatology” Melatonin can affect skin color, treat skin conditions, and may help with skin cancer.
34 citations
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June 2005 in “Journal of cosmetic dermatology” Medium-depth peels are safer and effective for improving skin appearance compared to deep peels.
October 2025 in “International Journal of Research in Dermatology” New laser technologies and methods are safer and more effective for hair removal on darker skin tones.
Melanocyte transplantation can safely restore skin color, especially in stable vitiligo, but must be chosen carefully based on the disease phase.
12 citations
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June 2010 in “Journal of dermatology” Some patients with severe alopecia areata developed skin darkening from their treatment, which may indicate a less effective response to the therapy.
June 2022 in “Endocrine Abstracts” Finasteride can cause lasting skin lightening in women.
76 citations
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January 2010 in “Journal of bone and mineral metabolism” 12 citations
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August 1988 in “Histopathology” The tumor likely shows dual neural crest differentiation.
11 citations
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August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which can be reversed with treatment.
3 citations
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September 2024 in “Journal of the American Academy of Dermatology” Dermatology datasets need more diversity in skin tones and ethnic representation.
6 citations
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February 2014 in “Human & experimental toxicology” Testosterone injections can cause skin darkening and thickening.
35 citations
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July 2007 in “Dermatologic clinics” Facial dark spots can be caused by the sun, genetics, makeup, or medicine, and are diagnosed by patient history and skin tests.
1 citations
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January 2009 in “Elsevier eBooks” Laser hair removal can be effective for darker skin but requires careful use to avoid side effects.
39 citations
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August 2005 in “Dermatologic surgery” Micropigmentation is a widely accepted tattooing technique for hiding cosmetic issues and medical uses, with permanent results and few side effects, but risks infection if not done with sterile tools.
2 citations
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January 2023 in “Dermatologic Therapy” CEFFE injections effectively and safely improve postinflammatory hyperpigmentation.