research Dissolving microneedles: an advanced approach for transdermal drug delivery
Dissolving microneedles offer efficient, minimally invasive drug delivery through the skin.
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research The Novel Excipient, Dodecyl-2-N, N-dimethylaminopropionate Hydrochloride (DDAIP-HCl) Improves the Flux of Minoxidil in Human Skin
DDAIP-HCl significantly increases minoxidil absorption into the skin.
research Profibrotic Molecules Are Reduced in CRISPR-Edited Emery–Dreifuss Muscular Dystrophy Fibroblasts
CRISPR gene editing reduces harmful molecules in cells from Emery–Dreifuss Muscular Dystrophy patients.
research Poloxam Thermosensitive Hydrogels Loaded with hFGF2-Linked Camelina Lipid Droplets Accelerate Skin Regeneration in Deep Second-Degree Burns
The hydrogels improved healing in deep second-degree burns.
research Reconsidering the Polycystic Ovary Syndrome (PCOS)
PCOS should be reclassified into two types based on hormone levels and symptoms.
research Scalp immersion proxigraphy (SIP): an improved imaging technique for phototrichogram analysis*
SIP is a better method for measuring hair growth accurately.
research Physicochemical Characterization of Chitosan-Decorated Finasteride Solid Lipid Nanoparticles for Skin Drug Delivery
Chitosan-decorated nanoparticles can improve skin delivery and reduce side effects of finasteride.
research Biological activity of novel progesterone derivatives having a bulky ester side chains at C-3
The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.
research Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time
Advanced imaging methods have improved understanding of cancer cell interactions and treatment strategies.
research Hair Growth-Promoting Activity of Hair Tonic containing Delipidated Ethanol Extract of Capsicum frutescens L. Leaves on Male Rabbit (Oryctolagus cuniculus)
The hair tonic with Capsicum frutescens extract helps hair grow in male rabbits.
research Differential wetting characterization of hair fibers.
The new method can tell how hair fibers react to moisture after treatments.
research A novel purification procedure for keratin-associated proteins and keratin from human hair
A new method effectively separates keratin-associated proteins and keratin from human hair.
research Hypoxia-preconditioned ADSC exosomes encapsulated in a multifunctional dual-network hydrogel promote the healing and functional regeneration of seawater-immersed wounds
The hydrogel helps heal seawater-immersed wounds by reducing infection and inflammation.
research Unlocking Dithranol’s Potential: Advanced Drug Delivery Systems for Improved Pharmacokinetics
Advanced delivery systems can make dithranol more effective and less irritating for treating psoriasis.
research DESIGN OF A VALIDATED HPTLC METHODOLOGY FOR THE MEASUREMENT OF LINOLEIC AND OLEANOLIC ACID IN ECLIPTA ALBA
The HPTLC method is effective and accurate for measuring linoleic and oleanolic acid in Eclipta alba.
research Las alteraciones metabólicas y funcionales asociadas a la COVID-19
Lower LDL-c levels predict higher COVID-19 mortality.
research Mechanistic insights into 5-aminolevulinic acid photodynamic therapy for acne vulgaris: targeting lipogenesis via the OLR1-Wnt/β-catenin pathway
5-aminolevulinic acid therapy reduces acne by decreasing fat production in skin cells.
research Distinguishing Lipedematous Scalp, Lipedematous Alopecia, and Diffuse Alopecia Areata
The conclusion is that it's important to tell apart alopecia areata from lipedematous alopecia for proper treatment, as alopecia areata can be reversed.
research Targeting PrfA from Listeria monocytogenes: a computational drug repurposing approach
The research suggests Dutasteride and Solifenacin may be effective against the bacterium causing listeriosis.
research Pathogenesis of pili annulati
Pili annulati is caused by a protein metabolism disorder affecting hair structure.
research Novel Quinazoline Derivative Induces Differentiation of Keratinocytes and Enhances Skin Barrier Functions against Th2 Cytokine-Mediated Signaling
SH-340 may improve skin barrier and help treat atopic dermatitis.
research (7E)-7,8-Dehydroheliobuphthalmin from Platycladus orientalis L.: Isolation, Characterization, and Hair Growth Promotion
DHHB from Platycladus orientalis L. promotes hair growth and could be a natural alternative to current treatments.
research Impaired turnover of autophagolysosomes in cathepsin L deficiency
Cathepsin L deficiency causes large, abnormal cell structures and health issues in mice.
research Chelators Depigment and Inorease Elasticity of Mink Skin
Certain chelators lighten mink skin and hair, increase skin elasticity, and disrupt hair growth without affecting fur quality.
research Formulation development of phospholipid structured carrier systems of methoxsalen and finasteride for skin diseases
research ToF‐SIMS characterization of the lipid layer on the hair surface. I: the damage caused by chemical treatments and UV radiation
Chemical treatments and UV radiation severely damage the lipid layer on hair.
research Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa
Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.
research Localized Hypotrichosis Type 1 Due to Intragenic Deletion of Exons 5-8 in Desmoglein Gene in a Neonate from Indian Family
A baby from an Indian family had a rare genetic disorder causing no scalp or body hair due to a specific gene deletion.
research Lineage commitment of dermal fibroblast progenitors is controlled by Kdm6b‐mediated chromatin demethylation
Kdm6b is crucial for skin cell differentiation.
research Development of optimized self-nanoemulsifying lyophilized tablets (SNELTs) to improve finasteride clinical pharmacokinetic behavior
Improved tablets lead to faster, better drug absorption for hair loss treatment.