May 2026 in “Signal Transduction and Targeted Therapy” Thompson et al. have discovered that bone morphogenetic protein (BMP) signaling is crucial for the morphogenesis of rete ridges in mammalian skin, a process distinct from hair follicle and sweat gland formation. Through advanced sequencing techniques, the study shows that rete ridges develop postnatally in pigs and humans, contributing to increased epidermal thickness. BMP signaling is identified as a key factor in this process, independent of hair density, with implications for skin regeneration therapies. The study also highlights the regenerative ability of neonatal skin to form rete ridges, unlike adult skin, which tends to scar. However, the use of porcine and murine models limits the direct applicability of these findings to human clinical settings.
2 citations
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May 2021 in “International journal of molecular sciences” Stem cells from hair follicles in a special gel show strong potential for bone regeneration.
December 2022 in “Nature Communications” Bead-jet printing of stem cells improves muscle and hair regeneration.
24 citations
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August 2023 in “International Journal of Molecular Sciences” Platelet-rich fibrin shows promise in healing cartilage and joint injuries but needs more testing.
6 citations
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July 2025 in “Advanced Materials” Biomimetic cell membrane-coated scaffolds significantly enhance tissue regeneration by mimicking natural cellular environments.
11 citations
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December 2018 in “Bone” Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.
January 2006 in “Chinese Journal of Aesthetic Medicine” The new artificial derma is better for skin regeneration and biocompatibility.
7 citations
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December 1971 in “Calcified Tissue Research” Hair follicles in injured skin can quickly accumulate minerals, especially calcium and phosphorus.
1 citations
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November 2023 in “Biomaterials advances” Sponges made of soy protein and β-chitin with human cells from hair or fat can speed up healing of chronic wounds.
The hydrogel treatment speeds up healing of diabetic wounds.
94 citations
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December 2018 in “Dentistry Journal” Oral-derived stem cells can effectively regenerate bone and tissues in dental procedures.
243 citations
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October 2003 in “Developmental biology” Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.
11 citations
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July 2024 in “Biomimetics” Injectable biomimetic gels can help heal tissues and deliver drugs but need improvements in strength and delivery.
2 citations
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January 2023 in “Ceramics International” The 3D printed scaffold with SB216763 and copper helps heal wounds and regrow skin and hair.
March 2021 in “Research Square (Research Square)” Strontium ranelate helps cartilage growth by blocking a specific cell pathway.
Mineral deposits form in hair follicles after skin injury, faster in rats given DHT.
17 citations
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April 2017 in “PLoS ONE” Hair follicle cells can become bone-like cells, useful for bone repair.
April 2025 in “WORLD JOURNAL OF PLASTIC SURGERY” Stem cells improve healing of diabetic wounds.
1 citations
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January 2024 in “Advances in Engineering Technology Research” Bone marrow stem cells from Guizhou miniature pigs can grow well and become different cell types, useful for tissue engineering.
January 2026 in “Regenerative Biomaterials” Strontium and cerium are most effective for tissue repair.
3 citations
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July 2023 in “International Journal of Biological Macromolecules” The hydrogel helps heal wounds and regrow hair by mimicking a baby's environment.
64 citations
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August 2007 in “Artificial Organs” PHBV nanofiber matrices help wounds heal faster when used with hair follicle cells.
8 citations
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January 2024 in “Regenerative Biomaterials” The hydrogel effectively treats dental implant issues by killing bacteria, reducing inflammation, and improving implant success.
August 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Different types of skin cells create unique support structures that can affect skin cell growth and could help in skin repair.
46 citations
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May 2021 in “Stem Cell Research & Therapy” Strontium ranelate helps cartilage growth by blocking a specific cell pathway.
156 citations
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March 2022 in “Exploration” Bioactive inorganic particles-based biomaterials show promise for improving skin wound healing.
18 citations
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September 2013 in “Technology” The study introduced a new imaging technology to track skin healing and bone marrow cell activity over time.
132 citations
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April 2021 in “Stem Cell Research & Therapy” A special membrane with cell particles helps heal diabetic wounds faster.
44 citations
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January 2021 in “Research” MCSA hydrogels can effectively treat melanoma and aid wound healing.
March 2026 in “IP Indian Journal of Conservative and Endodontics” PRP shows promise for regenerating dental tissues.