research Major approaches of molecular and physiopathological mechanisms for hormonal treatment of melasma: a systematic review
Estrogens and progesterone are key in regulating melasma pigmentation.
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390-420 / 1000+ results research On the etiology of vitiligo and gray hair
Melanocytes are destroyed by factors needed for melanin production, causing vitiligo and gray hair.
research Zebrafish Model of Hereditary Pigmentary Disorders
Zebrafish help understand genetic causes of skin pigment disorders like albinism.
research Desmodesmus pannonicus Water Extract Inhibits Melanin Synthesis and Promotes Wound Healing
Desmodesmus pannonicus water extract may help reduce skin pigmentation, heal wounds, and promote hair growth.
research Tyrosinase inhibition due to interaction of homocyst(e)ine with copper: the mechanism for reversible hypopigmentation in homocystinuria due to cystathionine beta-synthase deficiency.
Lowering homocyst(e)ine levels can reverse skin and hair lightening by restoring enzyme activity needed for pigmentation.
research Single-hair follicular unit transplant for stable vitiligo
Follicular unit transplant successfully repigmented vitiligo patch on upper lip.
![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs](/images/research/4eb017dc-711d-4926-bcd0-c3b8f48e3a99/small/19974.jpg)
research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs
ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
research Finasteride inhibits melanogenesis through regulation of the adenylate cyclase in melanocytes and melanoma cells
Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
research Treatment of Corticosteroid-Induced Hypopigmentation Using Fractional Carbon Dioxide Laser
research Scalp Micropigmentation Is an Effective Treatment for Localized Alopecia: Technical Analysis and a Series of Ten Case Reports
Scalp micropigmentation effectively treats localized alopecia with high patient satisfaction.
research A function for Rac1 in the terminal differentiation and pigmentation of hair
Rac1 is essential for proper hair structure and color.
research Scalp Micropigmentation Procedure: A Useful Procedure for Hair Restoration
Scalp Micropigmentation is an effective and safe option for hair restoration and camouflaging scalp scars.
research BMI1 is required for melanocyte stem cell maintenance and hair pigmentation
BMI1 is essential for preventing hair greying and maintaining hair color.
research Metal-Chelation-Assisted Deposition of Polydopamine on Human Hair: A Ready-to-Use Eumelanin-Based Hair Dyeing Methodology
Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.
research Heterogeneity of neural crest-derived melanocytes
Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
research A proteoglycan-based topical treatment for hair greying: in vitro antioxidant and pro-melanogenic effects
PP-PTKL may help treat hair greying, but more testing is needed.
research The Efficacy of Platelet‐Rich Plasma in Facial Lichen Planus Pigmentosus: A Prospective Pilot Study
PRP treatment improved skin pigmentation and appearance in facial lichen planus pigmentosus.
research 464 Spatial transcriptomics links gene expression profiles to functional and structural traits of darkly pigmented skin
Dark skin has stronger barriers and structure due to specific gene activity.
research Patchy alopecia areata sparing gray hairs: a case series
Patchy alopecia areata can affect only pigmented hairs, leaving gray hairs untouched.
research De Novo Production of Dermal Papilla Cells during the Anagen Phase of the Hair Cycle
New cells are added to the hair's dermal papilla during the active growth phase.
research Hair follicle-derived melanocyte transplant as a promising treatment strategy for vitiligo
Hair follicle-derived melanocyte transplant could effectively treat vitiligo by restoring skin color.
research Synergistic delivery of ginseng exosomes and biomimetic melanosomes via temporally controlled hydrogel microneedles restrain the pathologic triad of vitiligo
A new microneedle treatment can effectively repigment skin in vitiligo.
research Punch graft versus follicular hair transplantation in the treatment of stable vitiligo
Punch grafting treats vitiligo faster but can cause a cobblestone look, while follicular hair transplantation is slower but looks better and has no side effects.
research Updates in Surgical Treatment of Vitiligo
Surgical treatments for vitiligo are improving to enhance results and reduce costs.
research Evolution in action: highlighting a role for the Agouti gene in development?
The Agouti gene influences pigmentation and may have a developmental role in deer mice.
research Intradermal Local Injection of Autologous Cell‐Free Fat Extract for the Treatment of Refractory Postinflammatory Hyperpigmentation
CEFFE injections effectively and safely improve postinflammatory hyperpigmentation.
research Effect on Growth Performance and Hair Color in Weanling Piglets by Iron Glycine Chelate with Different Purity
Adding 0.029% iron glycine chelate to piglet diets improves growth and hair color.
research Koebnerization secondary to microblading
A woman developed vitiligo from repeated eyebrow microblading.
research LB1258 Investigation of the role and mechanism of pigment epithelium-derived factor (PEDF) in androgenetic alopecia
Reducing PEDF may help treat hair loss.
research Decrypting the Potential of Nanotechnology-Based Approaches as Cutting-Edge for Management of Hyperpigmentation Disorder
Nanotechnology can improve treatments for skin discoloration.