September 2025 in “Therapies” Finasteride use for hair loss may cause depression and suicidal thoughts, requiring careful monitoring.
Men with sexual side effects from finasteride may face higher risks of depression and suicidal thoughts.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Acne treatment, including isotretinoin, improves quality of life and does not worsen depression.
January 2012 in “The Journal of Clinical Psychiatry”
April 2026 in “Brain Sciences” Finasteride may cause depression and suicidal thoughts, especially in young men.
September 2025 in “The Journal of Clinical Psychiatry” Finasteride may increase depression and suicide risks, needing better safety checks and informed consent.
August 2025 in “Asian Journal of Beauty and Cosmetology” Hair loss is linked to higher depression, especially in certain groups.
May 2025 in “Psychopharmacology” Chronic finasteride use in male rats doesn't strongly cause depression or anxiety due to adaptive stress hormone changes.
March 2025 in “Journal of Cosmetic Dermatology” Finasteride use may increase depression and suicide risk, especially at 1 mg, so monitoring is advised.
February 2025 in “Clinical Cosmetic and Investigational Dermatology” Genetic risk for hair loss can increase depression risk, but depression doesn't increase hair loss risk.
August 2024 in “Archives of Women s Mental Health” Women with PCOS have more depression and stress due to high androgen levels, not obesity or insulin resistance.
July 2024 in “International Journal of Reproduction Contraception Obstetrics and Gynecology” Depression is more common in infertile women with PCOS than those without.
April 2024 in “Research Square” Children with alopecia areata often experience more anxiety and depression, linked to neglectful family dynamics.
December 2023 in “Alzheimer's & dementia” Finasteride may help reduce anxiety and depression in elderly but might cause depression in young men.
November 2021 in “World Family Medicine Journal /Middle East Journal of Family Medicine” Women with PCOS are more likely to experience depression and have a negative body image compared to women without PCOS.
August 2019 in “Journal of the American Academy of Dermatology” Depression and hair loss may influence each other.
August 2012 in “Reactions Weekly” Finasteride users with sexual issues often experience depression.
November 2021 in “Frontiers in Genetics” The FAW-FS algorithm improves depression recognition, and psychological interventions help AGA patients' mental health.
June 2017 in “Reactions Weekly” Finasteride (Propecia) may cause depression and suicidal thoughts; stop use and inform a healthcare professional if symptoms develop.
69 citations
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April 2017 in “BMJ open” Many people with alopecia experience high levels of social anxiety, anxiety, and depression, and while wigs can boost confidence, they may also cause anxiety.
49 citations
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June 2012 in “Anais Brasileiros de Dermatologia” Hair loss in women is linked to higher depression symptoms.
6 citations
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January 2024 in “Journal of Cosmetic Dermatology” Alopecia areata patients have worse quality of life, anxiety, and depression than vitiligo patients.
5 citations
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August 2022 in “Psychology Research and Behavior Management” Hair loss in South Saudi Arabia adults often harms quality of life and leads to depression.
2 citations
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July 2019 in “Digital Showcase Research, Scholarship, & Creative Works (University of Lynchburg)” No proven link between isotretinoin and depression.
1 citations
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June 2025 in “European Journal of Clinical Pharmacology” Finasteride may increase the risk of suicidality and depression, especially in younger people.
1 citations
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April 2019 in “The Journal of urology/The journal of urology” Marijuana use is linked to higher chances of needing treatment for urinary symptoms in men over 40.
February 2026 in “Postgraduate Medicine” 5-alpha reductase inhibitors slightly increase depression risk, but the risk varies based on the control group used.
Gender-diverse individuals face more depression and anxiety, possibly due to unique stress profiles.
January 2026 in “Cronfa (Swansea University)” Finasteride and dutasteride may increase the risk of depression and suicidality, so patients should be monitored closely.
August 2025 in “medRxiv (Cold Spring Harbor Laboratory)” 5-alpha reductase inhibitors may increase depression risk by 31%, but results vary based on comparison groups.