September 2025 in “Turkish Journal of Dermatology” Oxidative stress may play a role in alopecia areata, but depression and suicide risk are similar to healthy peers.
Women with PCOS, especially with hirsutism, should be screened for depression and anxiety.
April 2023 in “Journal of Investigative Dermatology” Narrowband Ultraviolet B treatment can significantly reduce anxiety in psoriasis patients, but it doesn't significantly affect depression.
January 2013 in “Psychiatry and clinical neurosciences” Physical symptoms in depression can reveal underlying medical conditions.
Finasteride may cause depression and affect brain and gut health in male rats.
May 2017 in “Chinese Journal of Dermatology” Alopecia negatively affects quality of life and mental health.
25 citations
,
November 2013 in “PLoS ONE” Estrogen and androgen signals control synaptic changes in rat brains.
11 citations
,
May 2006 in “Journal of the European Academy of Dermatology and Venereology” Combining paroxetine and triamcinolone effectively treats both alopecia areata and depression.
October 2025 in “Reactions Weekly” September 2025 in “Journal of the American Academy of Dermatology” Deuruxolitinib improves anxiety and depression in severe alopecia areata patients.
August 2025 in “Libyan Medical Journal” People with vitiligo or alopecia areata have higher anxiety and depression than healthy people.
June 2024 in “British Journal of Dermatology” DLQI is a reasonable quality-of-life measure for alopecia patients, but more research is needed.
January 2018 in “Turkiye Klinikleri Journal of Medical Sciences” Alopecia areata treatment should consider life quality and mental health, not just clinical results.
February 2023 in “Cureus” Male pattern baldness in medical students is linked to higher depression, loneliness, and internet addiction.
March 2021 in “Iranian journal of public health” 10 citations
,
May 2021 in “Psychoneuroendocrinology” Testosterone levels aren't important for depression in men, but some other hormones might affect certain symptoms.
7 citations
,
January 2019 in “Brazilian Journal of Pharmaceutical Sciences” Maidenhair fern extract reduced anxiety and depression in rats and may work due to its antioxidant and anti-inflammatory properties.
3 citations
,
August 2020 in “Urology Journal” Using 5-alpha reductase inhibitors may increase the risk of mild depression.
3 citations
,
October 2018 in “Journal of Drug Delivery and Therapeutics” People with polycystic ovary syndrome often experience anxiety and depression.
1 citations
,
March 2023 in “Healthcare” Helping PCOS patients focus on hope and control can reduce depression.
1 citations
,
June 2022 in “International Journal of Health Sciences” Lower BDNF levels link to worse depression in alopecia areata patients.
1 citations
,
January 2022 in “Open Access Macedonian Journal of Medical Sciences” BDNF, TSH, fT4, anti-TPO, and 25-OH Vitamin D levels predict depression risk in patients with autoimmune thyroiditis and hypothyroidism.
1 citations
,
January 2021 in “European Journal of Inflammation” Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.
1 citations
,
January 2019 Higher testosterone in females with PCOS is linked to depression and cognitive issues, but anti-androgen treatment can help.
January 2025 in “The Atlantic Journal of Medical Science and Research” Many dermatology patients experience anxiety and depression, especially those with acne or psoriasis.
November 2024 in “Cureus” Combining therapy, behavior techniques, and medication can help manage trichotillomania and depression.
9 citations
,
April 2020 in “The Journal of Urology” 5α-Reductase inhibitors don't cause depression.
1 citations
,
August 2017 in “The Journal of urology/The journal of urology” 5α-reductase inhibitors may increase the risk of depression and suicidal thoughts.
April 2026 in “The Journal of Steroid Biochemistry and Molecular Biology”