research Facile and Efficient Enzymatic Methods for Harvesting or Removal of Cuticle Cells from Human Hair Shafts
The conclusion is that new methods for isolating hair cuticle cells and removing the cuticle layer are effective and convenient.
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research 312 CRISPR/Cas9-based targeted genome editing for correction of recessive dystrophic epidermolysis bullosa using iPS cells
The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.
research Key locations of oxidative damage in human hair keratins after heat and ultraviolet light exposure
Heat and UV exposure damage hair structure by altering keratins.
research Fiber-Safe Extraction of Red Mordant Dyes from Hair Fibers
Researchers developed a less damaging way to extract red dyes from wool using EDTA and DMF, preserving the fiber's strength for further analysis.
research External post mortem artefact: a key issue in hair result interpretation
Hair test results can be misleading due to contamination, so they shouldn't be used alone to determine drug use.
research Synthesis of 5α-Reductase Special inhibitor Finasteride
Finasteride is made through a series of chemical reactions starting from a specific intermediate compound.
research Trazodone by epigenetic mechanism can reverse the post finasteride syndrome
Trazodone might help reverse post finasteride syndrome.
research Sodium Valproate Improves Skin Flap Survival via Gamma-Aminobutyric Acid and Histone Deacetylase Inhibitory System
Sodium valproate helps skin healing by affecting GABA and histone deacetylase.
research New Synthesis of Finasteride
A new method to make Finasteride is more cost-effective and yields 16%.
research Reproduction Mechanism of SS Cross-Links in Permed Hair by the Washing after Reduction with Thioglycolic Acid
Washing permed hair after using thioglycolic acid helps reform strong bonds, making hair stronger.
research Antroquinonol Exerts Immunosuppressive Effect on CD8+ T Cell Proliferation and Activation to Resist Depigmentation Induced by H2O2
Antroquinonol may help prevent skin depigmentation by suppressing certain immune cells.
research Structure of human steroid 5α-reductase 2 with anti-androgen drug finasteride
The research helps understand how finasteride works and aids drug development.
research Voltammetric detection with a comprehensive electrochemistry study of minoxidil using nuclear magnetic resonance and infrared analyses: Applications in the forensic and pharmaceutical fields
A new, quick method accurately detects minoxidil in drugs and cosmetics.
research Functionalization of Alkenes with Difluoromethyl Nitrile Oxide to Access the Difluoromethylated Derivatives
A new method efficiently modifies alkenes to create useful medicinal compounds.
research Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
Histone demethylases can change gene expression and may be linked to diseases like cancer.
research (Un)targeted Scanning of Locks of Hair for Drugs of Abuse by Direct Analysis in Real Time–High-Resolution Mass Spectrometry
A new method can quickly and accurately detect drugs in hair.
research A genetic electrophoretic variant of high-sulfur hair proteins for forensic hair comparisons. II. Practical application of electrophoretic analysis of hair protein to forensic hair comparisons.
Electrophoresis can effectively analyze hair proteins for forensic use, even after cosmetic treatments and up to 2 years of weathering.
research Effective Penetration of the Oxidized Keratin‐Rebonding Materials Into Hair Shafts Based on Charge Conversion
Charge-conversion chemistry improves hair-rebonding by enhancing penetration and strength.
research Simultaneous determination of 30 hormones illegally added to anti-ageing functional foods using UPLC-MS/MS coupled with SPE clean-up
New method effectively detects illegal hormones in anti-aging foods.
research STEEL. IN: STRUCTURAL CONDITION ASSESSMENT
Targeting LPA could help treat skin disorders.
research Discoid lupus erythematosus successfully treated with deucravacitinib
Deucravacitinib may effectively treat discoid lupus erythematosus.
research Unraveling the Complex: Changes in Secondary Science Preservice Teachers' Assessment Expertise
Changes in early neurosteroid levels can affect adult learning and anxiety.
research A novel EDA variant that causes X-linked hypohidrotic ectodermal dysplasia in a Chinese family
A new EDA gene variant causes X-linked hypohidrotic ectodermal dysplasia in a Chinese family.
research A Neonate with Blisters
The newborn was diagnosed with a rare skin disorder causing blisters, which requires careful wound care and family support.
research Allergic contact dermatitis from dyes in wigs following diphencyprone treatment
Avoiding dyed wigs and clothing improved severe allergic reactions in a woman treated with diphencyprone.
research Photodegradation of human hair: a microscopy study
UV radiation significantly damages hair, especially with humidity, making it more vulnerable to further damage.
research Characterization of recombinant human liver dehydroepiandrosterone sulfotransferase with minoxidil as the substrate
Human liver enzyme DHEA ST helps process minoxidil.
research Pepsin Digestion for Proteomic Studies of the Human Hair Shaft
Pepsin digestion improves accuracy in analyzing proteins in human hair.
research Mutations in γ-secretase subunit–encoding PSENEN underlie Dowling-Degos disease associated with acne inversa
PSENEN gene mutations can cause both Dowling-Degos disease and acne inversa.
research AnnoPharma: Detection of substances responsible of ADR by annotating and extracting information from MEDLINE abstracts
AnnoPharma effectively identifies substances causing adverse drug reactions in medical abstracts.