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Did you mean dermal γδ T cells?

Glossarydermal γδ T cells

immune cells in skin that respond to pathogens quickly

Dermal γδ T cells are a type of immune cell found in the skin. They play a crucial role in the body's defense system by recognizing and responding to pathogens and damaged cells. Unlike the more common αβ T cells, γδ T cells have a unique T-cell receptor that allows them to respond quickly to a wide range of threats, contributing to skin health and wound healing.

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research Butyrophilin-like 2 (BTNL2) to the Rescue: controlling autoaggressive dermal gamma delta (GD) T lymphocytes in human hair follicles (HFs) 3747

November 2025 in “The Journal of Immunology”

BTNL2 helps protect hair follicles from immune attacks, which could aid in treating alopecia areata.

Perforin Expression by Cutaneous Gamma Delta T Cells

research Perforins Expression by Cutaneous Gamma Delta T Cells

13 citations , August 2020 in “Frontiers in Immunology”

Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.

research Editor's evaluation: Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage

June 2021

Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.

research SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells

330 citations , December 2009 in “Cell stem cell”

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

research Hormonal Effects on Hair Follicles

102 citations , July 2020 in “International journal of molecular sciences”

Hormones like testosterone and estrogen significantly affect hair growth and structure.

research Tissue engineering of skin and regenerative medicine for wound care

192 citations , January 2018 in “Burns & Trauma”

Current skin substitutes help heal severe burns but don't fully replicate natural skin features.

research Genome-wide association study in alopecia areata implicates both innate and adaptive immunity

717 citations , June 2010 in “Nature”

Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.

Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences Between Sox2-Positive and Sox2-Negative Cells In Vitro and In Vivo

research Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo

68 citations , December 2011 in “Journal of Investigative Dermatology”

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

Anti-PDGF Receptor β Antibody-Conjugated Squarticles Loaded with Minoxidil for Alopecia Treatment by Targeting Hair Follicles and Dermal Papilla Cells

research Anti-PDGF receptor β antibody-conjugated squarticles loaded with minoxidil for alopecia treatment by targeting hair follicles and dermal papilla cells

17 citations , May 2015 in “Nanomedicine: Nanotechnology, Biology and Medicine”

Scientists created tiny particles loaded with a hair growth drug, minoxidil, that specifically target hair follicles and skin cells to potentially improve hair growth.

research A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth

101 citations , March 2019 in “Cell Stem Cell”

Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.

research Rescuing key native traits in cultured dermal papilla cells for human hair regeneration

30 citations , November 2020 in “Journal of Advanced Research”

Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.

research Gene Expression in Rat Dermal Papilla Cells: Analysis of 2529 ESTs

14 citations , October 2000 in “Genomics”

Rat dermal papilla cells have unique genes crucial for hair growth.

Detecting the Mechanism Behind the Transition from Fixed Two-Dimensional Patterned Sika Deer (Cervus Nippon) Dermal Papilla Cells to Three-Dimensional Pattern

research Detecting the Mechanism behind the Transition from Fixed Two-Dimensional Patterned Sika Deer (Cervus nippon) Dermal Papilla Cells to Three-Dimensional Pattern

2 citations , April 2021 in “International Journal of Molecular Sciences”

The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.

Induction of Dermal Fibroblasts into Dermal Papilla Cell-Like Cells in Hydrogel Microcapsules for Enhanced Hair Follicle Regeneration

research Induction of dermal fibroblasts into dermal papilla cell-like cells in hydrogel microcapsules for enhanced hair follicle regeneration

4 citations , August 2020 in “Applied Materials Today”

Hydrogel microcapsules help create cells that boost hair growth.

LncRNA-PCAT1 Maintains Characteristics of Dermal Papilla Cells and Promotes Hair Follicle Regeneration by Regulating miR-329/Wnt10b Axis

research LncRNA-PCAT1 maintains characteristics of dermal papilla cells and promotes hair follicle regeneration by regulating miR-329/Wnt10b axis

13 citations , April 2020 in “Experimental Cell Research”

PCAT1 helps hair growth by controlling miR-329/Wnt10b.

research AIMP1-Derived Peptide Secreted from Hair Follicle Stem Cells Promotes Hair Growth by Activating Dermal Papilla Cells

5 citations , October 2024 in “International Journal of Biological Sciences”

A peptide from hair follicle stem cells can boost hair growth.

Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth

research Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth

256 citations , October 2013 in “Proceedings of the National Academy of Sciences of the United States of America”

Growing human skin cells in a 3D environment can stimulate new hair growth.

research Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation

71 citations , January 2019 in “International journal of biological sciences”

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

research Reprogramming of Human Hair Follicle Dermal Papilla Cells into Induced Pluripotent Stem Cells

26 citations , February 2012 in “Journal of Investigative Dermatology”

Human hair follicle cells can be successfully transformed into different types of cells, but not more efficiently than other adult cells.

Titrated Extract of Centella Asiatica Increases Hair Inductive Property Through Inhibition of STAT Signaling Pathway in Three-Dimensional Spheroid Cultured Human Dermal Papilla Cells

research Titrated extract ofCentella asiaticaincreases hair inductive property through inhibition of STAT signaling pathway in three-dimensional spheroid cultured human dermal papilla cells

13 citations , October 2017 in “Bioscience, Biotechnology, and Biochemistry”

Centella asiatica extract may help promote hair growth by blocking a specific cell signaling pathway.

research Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species

6 citations , September 2009 in “European journal of histochemistry”

CD90 is present on specific cells in dog hair follicles.

research Hair follicle dermal stem cells and skin‐derived precursor cells: Exciting tools for endogenous and exogenous therapies

30 citations , April 2017 in “Experimental Dermatology”

Hair follicle stem cells and skin cells show promise for hair and skin therapies but need more research for clinical use.

research Human αβ and γδ T Cells in Skin Immunity and Disease

83 citations , June 2018 in “Frontiers in immunology”

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

research Regulatory T-Cells: Potential Regulator of Tissue Repair and Regeneration

188 citations , March 2018 in “Frontiers in Immunology”

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

research Identification of key genes induced by platelet-rich plasma in human dermal papilla cells using bioinformatics methods

16 citations , December 2016 in “Molecular Medicine Reports”

Platelet-rich plasma may help hair follicle cells grow by affecting certain genes and pathways.

research Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions

7 citations , June 2021 in “Cell Proliferation”

Low oxygen levels improve the function of hair and skin cells when they are in direct contact.

research Balding hair follicle dermal papilla cells contain higher levels of androgen receptors than those from non-balding scalp

227 citations , January 1998 in “Journal of Endocrinology”

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

research Identification of Androgen-Inducible TGF-β1 Derived from Dermal Papilla Cells as a Key Mediator in Androgenetic Alopecia

78 citations , June 2003 in “Journal of Investigative Dermatology Symposium Proceedings”

TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.

Sphere Formation Increases the Ability of Cultured Human Dermal Papilla Cells to Induce Hair Follicles from Mouse Epidermal Cells in a Reconstitution Assay

research Sphere Formation Increases the Ability of Cultured Human Dermal Papilla Cells to Induce Hair Follicles from Mouse Epidermal Cells in a Reconstitution Assay

75 citations , August 2011 in “Journal of Investigative Dermatology”

Forming spheres boosts the ability of certain human cells to create hair follicles when mixed with mouse skin cells.

research Methods for the isolation and 3D culture of dermal papilla cells from human hair follicles

55 citations , April 2017 in “Experimental Dermatology”

The document describes a way to isolate and grow human hair follicle cells in 3D to help study hair growth.