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GlossaryDermal Thickness

measurement of the skin's middle layer depth

Dermal thickness refers to the measurement of the depth of the dermis, which is the middle layer of the skin situated between the epidermis (outer layer) and the subcutaneous tissue (inner layer). It plays a crucial role in skin health, influencing factors like elasticity, strength, and the ability to retain moisture. Variations in dermal thickness can affect how the skin responds to aging, injury, and various dermatological conditions.

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Reepithelialization of a Full-Thickness Burn from Stem Cells of Hair Follicles Micrografted into a Tissue-Engineered Dermal Template (Integra)

research Reepithelialization of a Full-Thickness Burn from Stem Cells of Hair Follicles Micrografted into a Tissue-Engineered Dermal Template (Integra)

87 citations , February 2004 in “Plastic and Reconstructive Surgery”

Hair follicle stem cells helped heal a severe scalp burn without needing traditional skin grafts.

Microporous Dermal-Mimetic Electrospun Scaffolds Pre-Seeded with Fibroblasts Promote Tissue Regeneration in Full-Thickness Skin Wounds

research Microporous Dermal-Mimetic Electrospun Scaffolds Pre-Seeded with Fibroblasts Promote Tissue Regeneration in Full-Thickness Skin Wounds

62 citations , March 2015 in “PLOS ONE”

Pre-seeding scaffolds with fibroblasts improves skin wound healing.

research Prevascularization of dermal substitutes with adipose tissue-derived microvascular fragments enhances early skin grafting

57 citations , July 2018 in “Scientific Reports”

Using adipose tissue-derived fragments improves early skin graft success.

Evidence That 1 Percent Meshushit Ointment Prevents Progressive Dermal Ischemia of Experimental Deep Partial Skin Thickness Burns: A Preliminary, Quantitative Controlled Study

research Evidence that 1 per cent Meshushit ointment prevents progressive dermal ischaemia of experimental deep partial skin thickness burns: a preliminary, quantitative controlled study

February 1989 in “Burns”

Meshushit ointment helps form thicker healing tissue and preserves hair follicles in burns.

research Stem cells of hair follicles micrografted into a tissue-engineered dermal template (Integra®)

December 2006 in “Burns”

The treatment successfully integrated hair follicles into a dermal template, showing new hair growth and blood vessel formation.

research Menopause and Dermal White Adipose Tissue Depletion: Mechanistic Links, Adipogenesis, and Regenerative Therapeutic Replacement

January 2026 in “Journal of Cosmetic Dermatology”

Menopause reduces skin fat, but treatments like magnolol and PLLA-SCA can help restore skin health.

research Anagen hair follicles transplanted into mature human scars remodel fibrotic tissue

6 citations , January 2023 in “npj regenerative medicine”

Transplanting growing hair follicles into scars can help regenerate and improve scar tissue.

research 3D bioprinting of a gelatin-alginate hydrogel for tissue-engineered hair follicle regeneration

15 citations , March 2022 in “Acta Biomaterialia”

The new 3D bioprinting method successfully regenerated hair follicles and shows promise for treating hair loss.

research Anagen Hair Follicles Transplanted into Mature Human Scars Remodel Fibrotic Tissue

1 citations , January 2021 in “SSRN Electronic Journal”

Transplanted hair follicles can improve and remodel mature scars.

research [Skin tissue engineering in China].

1 citations , October 2008 in “PubMed”

China made major progress in creating artificial skin for better burn treatment.

research Skin connective tissue and ageing

77 citations , July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology”

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

research Single-stage transplantation combined with epidermal stem cells promotes the survival of tissue-engineered skin by inducing early angiogenesis

11 citations , March 2023 in “Stem Cell Research & Therapy”

Epidermal stem cells improve skin graft survival by promoting early blood vessel formation.

research Activating autophagy promotes skin regeneration induced by mechanical stretch during tissue expansion

January 2024 in “Burns and trauma”

Activating autophagy helps skin regenerate better during tissue expansion.

ADM Scaffolds Generate a Pro-Regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1

research ADM Scaffolds Generate a Pro-regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1

17 citations , June 2018 in “Frontiers in Physiology”

ADM scaffolds help skin heal by promoting a healing-type immune response.

research Injectable Biostimulator in Adipose Tissue: An Update and Literature Review

November 2025 in “Scientia Pharmaceutica”

Injectable biostimulators can improve skin by boosting collagen and fat cell activity, but more research is needed to confirm their safety and effectiveness.

research Hair follicle bulge-derived stem cells promote tissue regeneration during skin expansion

27 citations , October 2020 in “Biomedicine & Pharmacotherapy”

Hair follicle stem cells help skin heal and grow better.

The Regulatory Role of the Tetrapeptide AcSDKP in Skin and Hair Physiology and the Prevention of Aging Effects in These Tissues – A Potential Cosmetic Role

research The regulatory role of the tetrapeptide AcSDKP in skin and hair physiology and the prevention of ageing effects in these tissues – a potential cosmetic role

13 citations , March 2013 in “International Journal of Cosmetic Science”

AcSDKP may help prevent skin and hair aging and promote their growth.

research 946 Therapeutic effect of combined platelet-rich plasma strategies on morphea

April 2019 in “Journal of Investigative Dermatology”

Combining platelet-rich plasma injections and gel may effectively treat morphea, improving skin elasticity and reducing pain.

research 820 Filling Injection of Platelet-rich Plasma Gel as A New Method to Treat En Coup de Sabre Scleroderma

June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology”

Platelet-rich Plasma Gel may help treat en coup de sabre scleroderma, improving symptoms and skin quality with minimal side effects.

research Increment of growth factors in mouse skin treated with non-thermal plasma

18 citations , January 2018 in “International journal of medical sciences”

Non-thermal plasma treatment makes mouse skin thicker and increases growth factors without harming the tissue.

research Advanced therapies of skin injuries

28 citations , September 2015 in “Wiener Klinische Wochenschrift”

New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.

Histological Study on the Effect of Hyaluronic Acid Injection on the Skin of Adult and Aged Albino Rats

research Histological Study on the Effect of Hyaluronic Acid Injection (Dermal Filler) on the Skin of the Adult and Aged Albino Rat

June 2019 in “The Egyptian Journal of Histology”

Hyaluronic acid injections improve skin thickness and quality, protecting against aging in rats.

research The utility of elastic Verhoeff-Van Gieson staining in dermatopathology

38 citations , December 2012 in “Journal of Cutaneous Pathology”

EVG staining is a valuable, simple, and cost-effective method for diagnosing various skin conditions in dermatopathology.

Burn Reconstruction: The Problems, Techniques, and Applications

research Burn Reconstruction: the Problems, the Techniques, and the Applications

55 citations , October 2009 in “Clinics in Plastic Surgery”

Burn reconstruction improves with new techniques, materials, and tissue engineering.

research Dermal Changes in Osteoporosis Following Prolonged Treatment with Human Growth Hormone

9 citations , October 1976 in “Journal of Cutaneous Pathology”

Human growth hormone treatment improved skin thickness and structure in osteoporosis patients.

research Faculty Opinions recommendation of De novo production of dermal papilla cells during the anagen phase of the hair cycle.

December 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

New cells join the hair's dermal papilla during the growth phase, possibly affecting hair thickness.

Effect of Deep Dermal Tissue Dislocation Injury on Skin Fibrosis in Pigs

research P196 : Effects of different electrical parameter settings on hair growth: the changes of dermal papilla cell in vitro and at microscopic level in animal tissue

January 2014 in “프로그램북(구 초록집)”

Certain electrical settings can boost hair growth.