research Skin aging and barrier dysfunction: bridging current therapies with future genetic and nanotechnological interventions
Nanotechnology in skincare can precisely deliver anti-aging genes to improve skin health.
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research Direct conversion of mouse and human fibroblasts to functional melanocytes by defined factors
Fibroblasts can be turned into melanocytes for potential skin treatments.
research Melatonin Exerts Prominent, Differential Epidermal and Dermal Anti-Aging Properties in Aged Human Eyelid Skin Ex Vivo
Melatonin helps reduce aging signs in human eyelid skin.
research Evaluation of a Novel Dermal Cooling System for the Treatment of Benign Pigmented Lesions in Asians
The cooling system effectively and safely treats benign pigmented lesions in Asians.
research Dynamics and Epigenetics of the Epidermal Differentiation Complex
Epigenetic mechanisms control skin development by regulating gene expression.
research 588 Skin fibroblast heterogeneity and plasticity are determined by the local niche
Mouse skin fibroblasts vary in function and adaptability based on their environment.
research 709 Synthetic developmental tissue engineering of human hair follicles
Scientists have found a way to grow hair follicles from human cells in a lab, which could help treat hair loss and skin damage.
research Koebnerization secondary to microblading
A woman developed vitiligo from repeated eyebrow microblading.
research Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts
Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.
research An injectable photocuring silk fibroin-based hydrogel for constructing an antioxidant microenvironment for skin repair
The hydrogel speeds up wound healing and improves skin repair better than commercial options.
research 773 Generation of human hair follicle organoids in vitro and ex vivo by co-culture of primary human hair matrix keratinocytes and dermal papilla fibroblasts
Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.
research An epidermis‐permeable dipeptide is a potential cosmetic ingredient with partial agonist/antagonist activity toward fibroblast growth factor receptors
Pro-Ile could be used in cosmetics to improve skin, hair growth, and healing.
research A single type of progenitor cell maintains normal epidermis
One type of progenitor cell can maintain normal skin in mice.
research Skin & Hair Developmental Biology
research 837 Micro-regional transcriptome reveals local dermal-epidermal intercorrelation in atopic dermatitis
Atopic dermatitis shows a link between skin layers in inflammation, detectable with detailed gene analysis.
research Targeting receptor–regulator interactions
New treatments for cancer and skin disorders show promise in disrupting harmful cell interactions and promoting hair growth.
research Large-scale cultivation of transplantable dermal papilla cellular aggregates using microfabricated PDMS arrays
Researchers developed a method to grow hair follicle cells for transplantation using a special chip.
research Follicular dermal papilla structures by organization of epithelial and mesenchymal cells in interfacial polyelectrolyte complex fibers
Scientists created 3D hair-like structures that could help study hair growth and test treatments.
research Hormonal Therapies in Cosmetic Dermatology: Mechanisms, Clinical Applications, and Future Perspectives
Hormonal therapies can improve skin issues by adjusting hormone levels, with future advancements promising better results.
research Murine skin as a target for melatonin bioregulation
Melatonin affects mouse skin and may regulate skin functions.
research Epidermal growth factor, innovation and safety
Recombinant human epidermal growth factor is versatile, effective, and safe for long-term skin and mucosal treatments.
research Culture of hair matrix and follicular keratinocytes
research Matrix Metalloproteinase-19 Expression in Normal and Diseased Skin: Dysregulation by Epidermal Proliferation
MMP-19 may worsen skin diseases by affecting skin growth and inflammation.
research Exosomes in Dermatology.
Exosomes show promise for improving skin health and healing.
research Comparison of Epidermal Growth Factor Binding and Receptor Distribution in Normal Human Epidermis and Epidermal Appendages
research Polyclonal origin and hair induction ability of dermal papillae in neonatal and adult mouse back skin
Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.
research [Skin-like structure generated from implantation of hair follicle bulb cells into collagen/chitosan porous scaffolds in vitro].
Hair bulb cells can create skin-like tissues for potential skin repair.
research Skin structure
Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
research 1429 Proteomic analysis of cultured dermal papilla, dermal sheath and dermal fibroblast cells from female scalp highlights alterations in the cell populations with increasing age
Protein analysis shows aging changes in scalp cell types from women.
research 1422 Uncoupling desmosomal cadherin adhesion activates quiescent hair follicle stem cells and orchestrates self-organized regeneration through outside-in signaling
Disrupting a specific protein's function in hair follicle stem cells triggers their activation and a self-healing process.