research Topical Retinoids: Therapeutic Mechanisms in the Treatment of Photodamaged Skin
Topical retinoids effectively improve photodamaged skin.
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research Compatibility of Caffeine Clobetasol Propionate Dutasteride Nicotinamide and Progesterone in TrichoFoam™, a Natural Vehicle for Hair Foams.
TrichoFoam™ is a stable option for personalized hair loss treatment with most ingredients remaining effective for 90-180 days.
research Exploring the Relationship Between Ichthyosis and Scalp Paresthesia: Potential Connection and Treatment Approach with Fluocinolone
Fluocinolone may help treat scalp symptoms in ichthyosis patients.
research Topical and intralesional therapies for alopecia areata
No treatments fully cure or prevent alopecia areata; some help but have side effects or need more research.
research Ketoconazole Shampoo for Seborrheic Dermatitis of the Scalp: A Narrative Review
Ketoconazole shampoo is a safe and effective treatment for scalp seborrheic dermatitis.
research Letters to Dermatology
Stopping forehead irritation and using hydrocortisone helped a man's skin, Martinique has lower melanoma rates, a man had an allergy to a specific antifungal, another had unexplained cysts, certain drugs can cause skin reactions without always being interrelated, a link between Fanconi anemia and a skin condition was suggested, high levels of a certain protein may play a role in a type of psoriasis, and there's a need to study the connection between scalp pain and hair loss.
research Efficacy and safety of topical rosuvastatin & melatonin vs. placebo in patients with mild to moderate plaque psoriasis: A preliminary randomized double‐blinded clinical trial
Topical rosuvastatin and melatonin creams significantly reduce psoriasis severity and are safe.
research Clinical Quiz No. 2
Dermatophycosis is a treatable fungal skin infection spread by contact with infected animals.
research Pemphigus Foliaceus in a 26-year-old Hackney Pony
The pony's skin condition improved significantly with prednisolone treatment.
research Discoid lupus erythematosus exacerbated by contact dermatitis caused by use of squaric acid dibutylester for topical immunotherapy in a patient with alopecia areata
Topical squaric acid dibutylester worsened discoid lupus erythematosus in a patient.
research Development and evaluation of cosmeceutical cream for acne vulgaris
The cream effectively treats acne without causing irritation.
research Identification of novel step‐up regimen of intralesional triamcinolone acetonide in scalp alopecia areata based on a double‐blind randomized controlled trial
Start with 2.5 mg/mL triamcinolone acetonide for scalp alopecia areata and increase if needed.
research Combined microneedling with topical vitamin D3 or bimatoprost versus microneedling alone in the treatment of alopecia areata: A comparative randomized trial
Combining microneedling with either vitamin D3 or bimatoprost improves hair regrowth more than microneedling alone.
research Plain Language Summaries
Most clinicians follow discharge guidelines, many lupus patients don't use sunscreen regularly, dithranol is effective for psoriasis, biopsy methods should be based on lesion type, voriconazole may raise skin cancer risk, a new scale can help diagnose female hair loss early, and most melanomas may develop from existing moles.
research Topical Tacrolimus, Clobetasol, and Minoxidil (TCM) for Primary Cicatricial Alopecias: A Retrospective Analysis of Clinical Outcomes and Safety
TCM is an effective and safe treatment for primary cicatricial alopecias.
research Role of epidermal stem cells in repair of partial-thickness burn injury after using Moist Exposed Burn Ointment (MEBO®) histological and immunohistochemical study
MEBO ointment helps activate and grow skin stem cells for burn healing.
research Novel micelle formulations to increase cutaneous bioavailability of azole antifungals
New micelle solutions greatly improve skin delivery of certain antifungal drugs.
research A Comparison of the Efficacy, Relapse Rate and Side Effects among Three Modalities of Systemic Corticosteroid Therapy for Alopecia Areata
imTA and pulse therapy are effective for alopecia areata with manageable side effects, but relapse rates need improvement.
research Off-label uses of retinoids in dermatology
Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.
research Atypical Morphological Patterns of Topical Steroid-Modified Dermatophytosis: A Cross-Sectional Study in South Asia
The study conducted on 1,000 patients in South Asia highlights that the misuse of topical steroids has significantly altered the clinical presentation of dermatophytosis, leading to atypical, extensive, chronic, and recurrent infections. The most common atypical morphologies observed were ill-defined erythematous plaques, extensive concentric lesions, and pseudo eczematous plaques. The study found a significant association between prolonged steroid use and the severity of the disease. The findings underscore the need for regulatory control of steroid combinations, public education, and increased clinician awareness to address the growing issue of steroid-modified dermatophytosis.
research Combination of topical anthralin and calcipotriene in alopecia areata: A discussion of the mechanisms of action
Using anthralin and calcipotriene together might help treat tough cases of alopecia areata, but more research is needed to understand how it works.
research In vivo response of GsdmA3Dfl/+ mice to topically applied anti-psoriatic agents: effects on epidermal thickness, as determined by optical coherence tomography and H&E staining
Betamethasone dipropionate reduced skin thickness, fish oil increased it, and combined treatment had no significant effect.
research Use of adapalene in alopecia areata: Efficacy and safety of mometasone furoate 0.1% cream versus combination of mometasone furoate 0.1% cream and adapalene 0.1% gel in alopecia areata
Combining mometasone furoate cream with adapalene gel is safer and more effective for hair regrowth in alopecia areata than using the cream alone.
research Intralesional triamcinolone acetonide for alopecia areata: does dilution matter?
The best concentration of triamcinolone acetonide for treating alopecia areata is still unclear.
research Minoxidil
research Videodermoscopy in the evaluation of hair and scalp disorders
Videodermoscopy improves diagnosis of hair and scalp disorders and may reduce scalp biopsies.
research Minoxidil
Using minoxidil can cause severe skin reactions in some people.
research Corticosteroid Atrophy Plaque on the Scalp Treated with 5-Fluourouracil and Bleomycin Infusion in the MMP Technique
Hair regrowth was achieved using 5-Fluorouracil and Bleomycin for scalp atrophy caused by corticosteroids.
research Janus Kinase inhibitors in dermatology: a review
JAK inhibitors effectively treat skin conditions and topical forms are safer.
research Facial contact dermatitis due to spironolactone in an anti‐acne cream
Spironolactone in anti-acne cream can cause allergic skin reactions in some people.