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Desmocollin 1 and 3 have distinct patterns in human tissues, with Dsc1 in specific skin and hair layers and Dsc3 in various epithelial layers.

Desmocollin 1 helps maintain skin structure during fetal development.

A new genetic change in the DSC3 gene is linked to a rare condition causing hair loss and skin blisters in a child.

Desmosomal adhesion is essential for healthy skin structure and function.

A 4kb fragment of the desmocollin 3 promoter targets gene expression to specific skin and hair follicle areas.

Anti-Desmocollin 3 antibodies can cause pemphigus-like symptoms in mice.

Anti-Desmocollin 3 antibodies can cause atypical pemphigus symptoms.

A PKP1 gene mutation causes skin fragility and hair loss in Chesapeake Bay retriever puppies.

DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.

The research found that certain microRNAs are important for human hair growth and health.

Keratin 15 affects cell behavior and characteristics in skin cells.

Researchers found a new genetic mutation linked to a hair condition in a Japanese boy.

The endocannabinoid system affects oil production and inflammation in skin cells.

Zinc deficiency disrupts hair growth and cycle, but zinc supplements can fix this.

Desmoglein 1 can partly make up for the loss of Desmoglein 3 in hair adhesion but not in mucous membranes.

Keratin 10 end domains may increase skin cancer risk by reducing cell death.

Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.

Proteins influence the quality and traits of cashmere goat fleece, affecting hair strength and diameter.

Androgens increase growth factors in skin cells, which may lead to acne.

Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.

New mouse models of Pemphigus show severe symptoms and need better treatments.

Dermal papilla cells help skin stem cells grow into hair.

AD-derived keratinocytes effectively mimic inflammation in atopic dermatitis.

LEKTI is crucial for skin barrier and immune function, affecting conditions like Netherton syndrome and atopic dermatitis.

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.

A faulty KLHL24 gene leads to hair loss by damaging hair follicle stem cells.

Topical minoxidil helped an 8-year-old boy with a genetic hair disorder grow hair.

A new gene variant in the DSP gene is linked to a unique type of hair loss.