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A more sensitive assay was developed to detect enzyme activity converting arginine to citrulline in hair follicles.

Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.

Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.

Reconstructed skin models are useful for studying how skin processes certain chemicals.

HDAC1 is crucial for skin development and preventing tumors.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

Mice with the ab gene have abnormal sebaceous gland development, affecting sebum production.

Sebaceous glands help study fatty acid transporters and binding proteins.

Proteolytic enzymes damaged hair follicle stem cells in transgenic mice.

Abrocitinib, a JAK inhibitor, may help treat atopic dermatitis and alopecia universalis together.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

The TIP1 gene is crucial for normal plant cell growth in Arabidopsis.

A new mouse mutation causes skin and hair defects due to a gene change.

The protein's size was reduced, but more work is needed to confirm its function.

A potential treatment for atopic dermatitis could be to increase PADI1 expression to improve skin barrier function.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Mdm2 is crucial for controlling p53 to maintain healthy cells and prevent tumors.

A gene mutation in mice causes hair loss, weak bones, and protein buildup, showing how protein processing issues can lead to diseases.

Suppressing ODC activity reduces tumor growth in hair follicles.

Mutations in the ABCB6 gene cause Dyschromatosis Universalis Hereditaria.

Deucravacitinib led to full hair regrowth in a severe alopecia areata patient.

A new treatment called deucravacitinib helped a patient with severe hair loss grow their hair back quickly.

A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.

Histone demethylases can change gene expression and may be linked to diseases like cancer.

HtrA2 activity is crucial for normal hair growth by regulating fat cell development.

The newborn was diagnosed with a rare skin disorder causing blisters, which requires careful wound care and family support.

A truncated protein linked to breast cancer may change cell adhesion.