research Dual role of laminin‑511 in regulating melanocyte migration and differentiation
Laminin-511 is essential for proper melanocyte movement and development in mice.
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570-600 / 1000+ resultsresearch A WWP2–PTEN–KLF5 signaling axis regulates odontoblast differentiation and dentinogenesis in mice
WWP2 is crucial for tooth development in mice.
research 872 Dermal Wnt/β-catenin signaling controls hair follicle dermal condensate size during development
Dermal Wnt/β-catenin signaling is important for the proper size and development of hair follicles.
research c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny
c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.
research Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis
Deleting a specific protein in skin cells disrupts normal hair growth and development.
research Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture
Mechanical forces are crucial for shaping cells and forming tissues during development.
research Dermal Papilla Cells: From Basic Research to Translational Applications
Dermal papilla cells can help regrow hair and are promising for hair loss treatments.
research Afamin serum concentrations are associated with insulin resistance and metabolic syndrome in polycystic ovary syndrome
High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.
research Piperine reduces hair oiliness by inhibiting adipogenesis of hair stem cells
Piperine from black pepper can make hair less oily by blocking fat cell development in hair roots.
research Hair Vibrissa Follicle Morphogenesis is Linked to the Expression of Retinoic Acid Receptors α and γ Genes
Retinoic acid receptors are important for hair follicle development.
research The role of cathepsin E in terminal differentiation of keratinocytes
Cathepsin E is crucial for normal skin cell differentiation and development.
research Normal stem cells and cancer stem cells: similar and different
Deregulation of stem cell function is central to the development of some cancers.
research Regenerative Biology and Medicine
The book explains the science of tissue repair and regeneration, its medical uses, challenges, and ethical concerns.
research An eGFP-Col4a2 mouse model reveals basement membrane dynamics underlying hair follicle morphogenesis
Basement membrane changes are crucial for hair follicle development.
research Directed Expression of Keratin 16 to the Progenitor Basal Cells of Transgenic Mouse Skin Delays Skin Maturation
Keratin 16 delays skin maturation and affects skin and hair development in mice.
research Epidermal differentiation: The role of proteases and their inhibitors
Balanced protease activity is crucial for healthy skin and hair development.
research The biology and clinical application of systemic glucocorticoids
Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
research The Action of Hanson’s Thymus Extract on the Mouse
Hanson's thymus extract sped up growth and development in mice over generations.
research Development of polycystic ovary syndrome: involvement of genetic and environmental factors
PCOS is caused by both genetics and environmental factors like diet and obesity.
research Suprabasal Desmoglein 3 Expression in the Epidermis of Transgenic Mice Results in Hyperproliferation and Abnormal Differentiation
Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.
research 890 Development of pigmented reconstructed human epidermis model containing human melanoblasts from keratinocyte culture
The created skin model with melanoblasts improves the study of skin color and offers an alternative to animal testing.
research Reciprocal role of vitamin D receptor on β-catenin regulated keratinocyte proliferation and differentiation
Vitamin D receptor helps control skin cell growth and hair development.
research Loss of keratin 10 is accompanied by increased sebocyte proliferation and differentiation
Without keratin 10, there's more growth and development of oil-producing skin cells.
research Overexpression of human keratin 16 produces a distinct skin phenotype in transgenic mouse skin
High levels of human keratin 16 in mice cause skin lesions and abnormal skin development.
research Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia
Removing a specific gene in certain skin cells causes hair loss in mice by disrupting hair follicle development.
research Developmental origin of polycystic ovary syndrome - a hypothesis
The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.
research Smad7-Induced β-Catenin Degradation Alters Epidermal Appendage Development
Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.
research Developmental Mechanisms Controlling Cell Fate, Evolution of
The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.
research Apoptosis in human skin development: Morphogenesis, periderm, and stem cells
Apoptosis is essential for human skin development and forming a functional epidermis.
research Development and Prospects of Organ Replacement Regenerative Therapy
Scientists have made progress in creating replacement teeth, hair, and glands that work, which could lead to new treatments for missing teeth, baldness, and dryness conditions.