17 citations
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January 2015 in “MedChemComm” New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
17 citations
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August 2011 in “Current Medicinal Chemistry” New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.
17 citations
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March 2006 in “Journal of Cosmetic Dermatology” Hormonal changes during and after pregnancy can cause hair growth changes and hair loss, with treatments available for some conditions.
17 citations
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November 1997 in “Andrology” Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.
17 citations
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June 1996 in “The Journal of Steroid Biochemistry and Molecular Biology” FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.
17 citations
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May 1998 in “Steroids” Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.
16 citations
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January 2006 in “The Aging Male” Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.
15 citations
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March 2014 in “Molecular Medicine Reports” α-spinasterol from Melandrium firmum can help reduce prostate enlargement.
15 citations
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March 1997 in “International Journal of Dermatology” Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.
15 citations
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June 1995 in “The American Journal of the Medical Sciences” Finasteride caused enlarged breast tissue in a 62-year-old man.
15 citations
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June 1995 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride doesn't affect erections much, but may decrease libido in men.
14 citations
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February 2018 in “Psychoneuroendocrinology” Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.
14 citations
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September 2015 in “Expert Opinion on Therapeutic Targets” The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
13 citations
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December 2020 in “BMJ Open Diabetes Research & Care” Changes in SHBG levels don't predict diabetes risk reduction.
13 citations
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January 2019 in “Endocrine journal” Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.
12 citations
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May 2003 in “Journal of dermatological science” Hsc70 protein may influence hair growth by responding to androgens.
11 citations
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May 2024 in “Reproductive Biology and Endocrinology” Fetal ovaries produce different hormones than adult ovaries, and endocrine-disrupting chemicals may affect this process.
11 citations
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September 2020 in “OncoTargets and Therapy” Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.
11 citations
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July 2015 in “Gene” DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
11 citations
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December 2011 in “Revista Brasileira de Farmacognosia” The seeds of Abrus precatorius, when processed, can prevent hair loss more effectively than common treatments.
10 citations
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June 2010 in “Expert Opinion on Drug Metabolism & Toxicology” Finasteride reduces prostate cancer risk but may increase high-grade cancer chances.
10 citations
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February 2008 in “International Journal of Andrology” A combination of nanomilled oral testosterone and dutasteride normalized testosterone levels in men with low testosterone and is safe for short-term use.
10 citations
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April 2000 in “Archives of Oral Biology” Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.
10 citations
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June 2019 in “International Journal of Cosmetic Science” Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.
8 citations
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February 2025 in “Swiss Medical Weekly” Integrating best practices for steroid users in Swiss primary care is feasible and beneficial, but doping laws need change.
8 citations
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September 2024 in “Portuguese Journal of Dermatology and Venereology” Early treatment of PCOS is crucial for better health and quality of life.
8 citations
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June 2019 in “Scientific Reports” Increased PPARGC1α relates to hair thinning in common baldness.
8 citations
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July 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” DHT affects testicular development and regulates spermatogenesis in some fish.
8 citations
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May 2011 in “Journal of Pharmacology and Experimental Therapeutics” Dosing time affects finasteride's effectiveness and safety in rats.
8 citations
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September 2010 in “Journal of Men's Health” Androgenic Alopecia, a common hair loss condition, can be effectively treated with finasteride and other treatments.