June 2025 in “Stem Cell Research & Therapy” Combining stem cells with ATP significantly boosts hair regrowth in mice with hair loss.
January 2025 in “Dermatologic Therapy” Targeting multiple pathways may improve treatments for androgenetic alopecia.
May 2024 in “Journal of clinical medicine” Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.
February 2024 in “Biomedicines” Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.
Natural compounds from Chinese herbs may safely promote hair growth and treat common hair loss.
February 2024 in “Molecules/Molecules online/Molecules annual” NMN could potentially treat hair loss by reducing oxidative stress and improving cell health.
February 2024 in “Heliyon” People with androgenetic alopecia have different lipid levels in their blood, which vary between men and women, and may be linked to a higher risk of metabolic syndrome.
January 2024 in “Biomedicines” Using stem cells from hair follicles to treat female hair loss is safe and effective after six months.
October 2023 in “Georgetown medical review” Finasteride and Dutasteride can improve hair growth in male baldness but may cause temporary sexual dysfunction and possibly affect fertility.
September 2023 in “Stem Cells International” Substances from fat-derived stem cells can promote hair growth and counteract hormone-related hair loss by activating a key hair growth pathway.
July 2023 in “JAAD International” Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.
March 2023 in “Translational Andrology and Urology” 5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.
April 2022 in “Molecules” Teak leaf extract contains compounds that could help treat hair loss.
April 2019 in “Journal of the Endocrine Society” Androgens and estrogens are crucial for insulin secretion in males.
January 2017 in “Indian journal of drugs in dermatology” Saw palmetto extract may help with hair loss and acne but needs more research on safety and long-term effects.
January 2003 in “Humana Press eBooks” Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.
April 2022 in “Journal of Investigative Dermatology” Androgenetic alopecia causes hair thinning due to increased androgen activity, treatable with minoxidil and finasteride.
219 citations
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October 2009 in “Steroids” 5α-reductase inhibitors, like Finasteride and Dutasteride, help manage benign prostatic hyperplasia.
168 citations
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January 2005 in “Journal of Investigative Dermatology” Male and female mice have different skin thickness, and hormones affect their skin and hair growth differently.
57 citations
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April 2009 in “The Journal of Steroid Biochemistry and Molecular Biology” Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.
48 citations
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February 2006 in “Molecular and Cellular Endocrinology” 5α-reductase inhibitors may reduce male fertility and could be used for male contraception.
21 citations
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December 2015 in “Development Growth & Differentiation” DHT is crucial for urethral formation, and its disruption can affect masculinization and lead to hypospadias.
16 citations
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October 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Dutasteride may protect the brain in early Parkinson's disease.
13 citations
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September 2013 in “Steroids” The DHT immunoassay is unreliable due to high cross-reactivity with testosterone.
12 citations
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June 2007 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” A reliable model for screening type II 5α-reductase inhibitors was created and validated.
5 citations
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June 2015 in “Chinese journal of natural medicines/Zhongguo tianran yaowu/Chinese Journal of Natural Medicines” Tripterygium wilfordii multiglycoside effectively reduced prostate enlargement in rats without harmful effects.
3 citations
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March 2025 in “Endocrine Connections” Higher DHT levels are linked to more acne in adolescents, especially boys.
2 citations
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November 2017 in “Biotechnology Letters” Researchers found four natural compounds that can change DHT levels in prostate cancer cells.
2 citations
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June 2022 in “Molecules” Connarus semidecandrus Jack extract promotes hair growth and thickness, reduces prostate cancer cell growth, and could potentially be used as a treatment for hair loss.
February 2026 in “Food Research International” Lactiplantibacillus plantarum ZJUIDS51 can help regrow hair and improve scalp health in androgenic alopecia.