COVID-19 may lead to severe skin necrosis without clear underlying causes, as seen in a diabetic patient who required leg amputation.
212 citations
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January 2017 in “Mediators of Inflammation” Stem cells show promise in speeding up wound healing and tissue regeneration.
110 citations
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April 2020 in “Advances in Wound Care” Nanotechnology shows promise for better chronic wound healing but needs more research.
24 citations
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January 2023 in “International Journal of Nanomedicine” Biomembrane-based hydrogels can effectively promote chronic wound healing.
10 citations
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July 2023 in “Pharmaceuticals” The gel with coral extract and pectin nanoparticles helps heal chronic wounds.
10 citations
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January 2023 in “Journal of Orthopaedic Surgery and Research” Panax notoginseng saponins with stem cells improve healing and reduce inflammation in diabetic ulcers.
6 citations
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July 2025 in “Frontiers in Microbiology” Imbalanced skin bacteria worsen diabetic foot ulcers, but adjusting them might improve healing.
38 citations
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March 2024 in “World Journal of Experimental Medicine” Obesity worsens wound healing, and more research is needed to understand why.
1425 citations
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September 2020 in “Open Biology” Better understanding of wound healing is needed to develop effective treatments for chronic wounds.
280 citations
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July 2018 in “Antioxidants” Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.
106 citations
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August 2021 in “Pharmaceuticals” Extracellular vesicles help heal skin wounds and could be used for better treatments.
56 citations
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November 2022 in “Biomolecules” Targeting macrophages may improve wound healing.
22 citations
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October 2024 in “Advanced Healthcare Materials” The hydrogel treatment speeds up healing of chronic wounds.
10 citations
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January 2024 in “Burns & Trauma” Adipose stem cell-derived exosomes greatly improve wound healing.
9 citations
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October 2024 in “Heliyon” Exosomes show promise for healing diabetic foot ulcers.
1 citations
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November 2021 in “European journal of medical and health sciences” Growth factors-rich plasma treatments can significantly speed up wound healing and tissue regeneration.
January 2026 in “Burns & Trauma” RNA modifications help heal wounds and could lead to new treatments.
February 2026 in “Veterinary Sciences” SPARC-modified stem cells significantly improve dog skin wound healing.
6 citations
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May 2023 in “International journal of molecular sciences” Collagen-enhanced mesenchymal stem cells significantly improve skin wound healing.
July 2025 in “Journal of Investigative Dermatology” Negative Pressure Wound Therapy reduces surgical site infections and speeds up healing.
245 citations
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April 2009 in “Circulation Research” CD133+ cells help heal diabetic ulcers by promoting blood vessel growth and activating Wnt signaling.
61 citations
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April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
33 citations
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February 2024 in “International Journal of Molecular Sciences” Understanding fibroblast issues in diabetic foot ulcers is key to creating better treatments.
10 citations
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August 2022 in “International Journal of Molecular Sciences” Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
2 citations
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October 2025 in “Chinese Medicine” Berberine delivery systems improve wound healing by enhancing bioavailability, reducing inflammation, and promoting tissue regeneration.
Compound 6 is a promising candidate for better wound healing.
The hydrogel speeds up wound healing and improves tissue repair.
August 2025 in “Materials Today Bio” The modified nanofibrous dressings effectively heal infected wounds by reducing bacteria and inflammation.
December 2024 in “Deleted Journal” New therapies show promise for wound healing, but more research is needed for safe, affordable options.
15 citations
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June 2020 in “Applied Materials Today” The SA-MS hydrogel is a promising material for improving wound healing and skin regeneration in diseases like diabetes and skin cancer.