32 citations
,
May 1987 in “The Journal of Clinical Endocrinology & Metabolism” Salivary testosterone is a better measure for hirsutism than serum testosterone.
13 citations
,
January 2005 in “Chemical and Pharmaceutical Bulletin” Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.
May 2022 in “Gastroenterology” Supplemental testosterone may lower liver cancer risk in hepatitis C patients.
136 citations
,
January 2004 in “Neuroscience” Testosterone increases seizure risk through its conversion to specific neurosteroids.
38 citations
,
October 2014 in “Current Opinion in Endocrinology, Diabetes and Obesity” 5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.
209 citations
,
March 1998 in “Biochemical and biophysical research communications” Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.
24 citations
,
January 2001 in “Dermatologic clinics” Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.
January 2009 in “Chemical Reagents” The method produces finasteride with a 92% yield.
4 citations
,
July 1983 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Certain hormones can reduce skin oil and hair growth, potentially helping treat acne and excessive hair in women.
8 citations
,
March 2008 in “Deutsche medizinische Wochenschrift/Deutsche Medizinische Wochenschrift” Adding estrogen increased bone mass in a transsexual man undergoing hormone therapy.
13 citations
,
August 1997 in “Steroids” Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.
10 citations
,
November 2018 in “Developmental Psychobiology” Hair can effectively measure DHEA and testosterone levels in children.
Testosterone's health effects are complex and not definitively understood.
21 citations
,
December 2012 in “Maturitas” Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.
21 citations
,
January 2021 in “Therapeutic Advances in Endocrinology and Metabolism” Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.
April 2014 in “The FASEB Journal” Testosterone reduces knee movement, while flutamide and finasteride increase it.
64 citations
,
January 1985 in “Clinical endocrinology” A combination of desogestrel and ethinyl oestradiol effectively reduces hair growth in hirsute women.
5 citations
,
January 1984 in “Journal of psychosomatic obstetrics and gynecology/Journal of psychosomatic obstetrics and gynaecology” The treatment reduced hair growth and testosterone in women with excess hair and had some effects on stress responses.
7 citations
,
August 1985 in “British journal of dermatology/British journal of dermatology, Supplement” Medroxyprogesterone acetate injections are more effective than topical ointment in treating excessive hair growth in women.
Testosterone therapy can safely and effectively treat symptoms like low libido and fatigue in women, especially after menopause.
68 citations
,
May 1991 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Both cyproterone acetate and spironolactone effectively reduce hair growth in women with hirsutism.
15 citations
,
February 2019 in “Internal Medicine Journal” Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.
78 citations
,
October 2003 in “Cochrane library” Cyproterone acetate with estradiol may subjectively improve excessive hair growth in women, but it's not clinically better than other treatments.
Cyproterone acetate is an effective treatment for women with acne, hair loss, and excessive hair growth.
13 citations
,
November 2010 in “Experimental Dermatology” Vitamin C derivative reduces hair loss-related protein in cells.
August 2019 in “Carolina Digital Repository (University of North Carolina at Chapel Hill)” DHT enhances androgen receptor activity more than testosterone, and MAGE-11 influences this activity through specific interactions.
49 citations
,
October 1988 in “The Journal of Clinical Endocrinology & Metabolism” Leuprolide effectively reduces hair growth in hirsute women at higher doses.
43 citations
,
August 2010 in “Expert Opinion on Investigational Drugs” Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
October 2022 in “Linköping University medical dissertations” The method shows hair testosterone levels reflect those in saliva, but are affected by various factors and may indicate a risk for heart attack.
3 citations
,
June 1996 in “PubMed” Finasteride may help reduce male hair loss and excessive hair growth by lowering DHT levels.