research Trichotillomania as a Manifestation of Dementia
Trichotillomania in dementia may be better treated with dopamine blockers like quetiapine than with SSRIs.
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930-960 / 1000+ resultsresearch May patients receiving 5-alpha-reductase inhibitors be in higher risk of COVID-19 complications?
Men on 5-alpha-reductase inhibitors might have worse COVID-19 outcomes.
research Minoxidil — An Alternative to Nephrectomy for Refractory Hypertension
Minoxidil effectively lowers blood pressure with few side effects.
research Correlation between Traditional Chinese Medicine Syndromes and Type 2 Myocardial Infarction in Critically Ill Patients with Pulmonary Disease
Patients with deficiency syndrome, especially qi deficiency, have a higher risk of type 2 heart attacks.
research Potential Impact of Medicare Part D in the End-Stage Renal Disease Population
Medicare Part D causes significant coverage and cost issues for end-stage renal disease patients.
research Comparison of pharmacokinetics and relative bioavailabilities of two kinds of finasteride tablets
research Short-term efficacy and safety of valproate sustained-release formulation in newly diagnosed partial epilepsy VIPe-study. A multicenter observational open-label study.
Valproate sustained-release is effective and generally safe for short-term treatment of new partial epilepsy.
research Comment on ‘Androgenetic alopecia is associated with increased scalp hardness’: role of phosphodiesterase inhibitors?
Drugs like PDEI may help hair disorders like AGA.
research NEW PROPRIETARY BRANDS: Cefaclor monohydrate
Lifestyle changes are more effective than medication for reducing type 2 diabetes risk.
research Safety and efficacy of transdermal testosterone for treatment of hypoactive sexual desire disorder
Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.
research Efficacy, safety and dose response of STS01, a topical controlled release nanoparticle formulation (dithranol/Prosilic), in adults with mild to moderate patchy alopecia areata: A randomised, double-blind, multicentre, phase 2 trial
STS01 1% effectively promotes hair regrowth with minimal side effects.
research Effects of High Flux Hemodialysis Combined with L-Carnitine on Microinflammation and Arteriovenous Fistula in Maintenance Hemodialysis Patients
High-flux hemodialysis with L-carnitine improves heart function, reduces inflammation, and enhances quality of life in patients.
research Anti-diabetic activity of Tridax procumbens
Tridax procumbens may help treat diabetes.
research Low-dose oral minoxidil for androgenetic alopecia is not associated with blood pressure changes in patients also taking other antihypertensive medications: A multi-center cohort study using TriNetX
Low-dose oral minoxidil doesn't affect blood pressure in patients taking blood pressure meds.
research [A case of hair loss induced by carbamazepine].
Carbamazepine caused hair loss in a man, which stopped after he stopped taking the drug.
research Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications
PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.
research Ligand Based 3D-QSAR Study on a Series of Steroidal Human 5α-Reductase Inhibitors
research The Biological Actions of Dehydroepiandrosterone Involves Multiple Receptors
DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
research Effect of dose reduction of dutasteride in combination with alpha-blockers in patients with lower urinary tract symptoms/benign prostatic enlargement
Taking dutasteride every other day works as well as daily and better preserves sexual function.
research A method for achieving blood pressure control expeditiously with oral minoxidil
Oral minoxidil effectively controls blood pressure quickly and safely.
research Ethnobotanical, Phytochemical, Toxicological, and Pharmacological Properties of Ziziphus lotus (L.) Lam.: A Comprehensive Review
Ziziphus lotus is a safe plant with potential health benefits, but more research is needed.
research 3P's (Pharmacokinetic, Pharmacodynamic, and Pharmacogenomic) of Valproate: What's New?
New information shows Valproate may protect the brain and reduce breathing failure risk but can cause liver damage and other side effects, with genetics affecting dosage needs.
research Associations of dietary indices with risk of all-cause and cardiovascular mortality in hypertensive adults
This study analyzed data from 13,230 hypertensive adults to evaluate the impact of six dietary indices on mortality risk. Over a median follow-up of 8.3 years, 2,420 deaths occurred, including 637 from cardiovascular diseases. Higher scores on the AHEI, DASH, HEI-2020, MED, and MEDI indices were linked to reduced all-cause mortality, while a proinflammatory diet (high DII scores) increased risk. The DASH diet uniquely reduced cardiovascular mortality. Time trend analysis showed declining adherence to DASH and a slight increase in MEDI scores. Key dietary components affecting mortality included dairy, whole grains, and fatty acids. The study concludes that healthy dietary patterns, particularly the DASH diet, significantly lower mortality risk in hypertensive patients, advocating for personalized dietary interventions.
research Bisphenol-A antagonizes the rapidly modulating effect of DHT on spinogenesis and long-term potentiation of hippocampal neurons
Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.
research Efectos del minoxidilo en formulación oral en pacientes barosensibles
Careful monitoring is needed when using oral minoxidil for hair loss due to potential side effects.
research Safety and efficacy of oral administrated cepharanthine in non-hospitalized, asymptomatic or mild COVID-19 patients: a Double-blind, randomized, placebo-controlled trial
Cepharanthine is safe but not effective in significantly reducing COVID-19 recovery time.
research Comparison of clinical trials with finasteride and dutasteride.
Dutasteride reduces DHT more than finasteride, but both drugs improve BPH symptoms similarly.
research Signal Detection for Adverse Events of Finasteride Using Korea Adverse Event Reporting System (KAERS) Database
research Repurposing of Drugs for Cardiometabolic Disorders: An Out and Out Cumulation
Existing drugs are being repurposed to treat cardiometabolic disorders, which is safer, faster, and cheaper than developing new drugs.
research Unraveling the mechanism of action of cepharanthine for the treatment of novel coronavirus pneumonia (COVID-19) from the perspectives of systematic pharmacology
Cepharanthine may help treat COVID-19 by targeting multiple pathways.