January 2025 in “Journal of the American Academy of Dermatology” Low-dose oral minoxidil alone is effective for treating hair loss, but combining it with dutasteride or finasteride may offer better results.
97 citations
,
November 1986 in “Journal of Steroid Biochemistry” Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
42 citations
,
December 2015 in “International Journal of Clinical Pharmacology and Therapeutics” The 0.25% finasteride solution, when applied once a day, effectively reduces scalp DHT, potentially minimizing sexual side-effects linked to a systemic DHT reduction.
March 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Dutasteride 0.5mg was found to be more effective than finasteride 1mg in treating male pattern hair loss, with similar side effects.
15 citations
,
July 2022 in “Nano Research” A cholesterol-free liposomal platform using protopanaxadiol effectively promotes hair growth and treats alopecia.
3 citations
,
June 2018 in “Bioorganic & medicinal chemistry” Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.
May 2022 in “Reactions Weekly” 23 citations
,
February 2010 in “European Journal of Medicinal Chemistry”
15 citations
,
January 1995 in “Archives of dermatological research” OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.
2 citations
,
January 2020 in “Evidence-based Complementary and Alternative Medicine” Hataedock treatment improved skin health and reduced atopic dermatitis symptoms by enhancing the skin barrier and reducing inflammation.
2 citations
,
November 2024 in “JCEM Case Reports” Inhaled substances in e-cigarettes can cause hormone imbalances similar to congenital adrenal hyperplasia.
11 citations
,
May 2010 in “Journal of Medicinal Chemistry” A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
19 citations
,
October 2017 in “European Journal of Pharmaceutics and Biopharmaceutics” The gel made of minoxidil and hydroxypropyl-β-cyclodextrin improves hair growth and is good for long-term use.
P-3074 effectively blocks scalp DHT better than oral finasteride.
October 2023 in “Benha Journal of Applied Sciences” Methotrexate and vitamin D3 are potentially more effective and safer than triamcinolone for treating localized alopecia areata.
August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Optimized microneedles promote hair regrowth better than minoxidil without safety risks.
February 2018 in “The Journal of Sexual Medicine” DA-9401 protects against hair loss, improves organ function, and prevents infertility caused by finasteride.
1 citations
,
January 2022 in “Brazilian Journal of Pharmaceutical Sciences” Minoxidil can be effectively encapsulated in coated nanovesicles for potential drug delivery.
June 2025 in “Pharmaceutics” Ethosomes with 30% ethanol effectively deliver dutasteride to hair follicles for treating hair loss.
5 citations
,
January 1997 in “PubMed” December 1990 in “PubMed” Topical 17 alpha-propylmesterolone increases hair cell growth in androgenetic alopecia.
1 citations
,
February 2022 in “The Journal of Urology” Certain drugs like Dutasteride and Finasteride might help fight SARS-CoV-2 by increasing levels of a steroid called DHEA, which can protect the heart and increase nitric oxide to counteract the virus.
4 citations
,
May 2011 in “Current Drug Discovery Technologies” A new liposomal system for applying dutasteride to the skin was developed, showing better skin absorption and stability, potentially improving treatment for hair loss.
7 citations
,
January 2022 in “Bioengineering” The formulation with oleic acid may be better for treating male pattern baldness.
57 citations
,
May 1986 in “Clinics in endocrinology and metabolism” Androstanediol glucuronide is a reliable marker for hirsutism in women.
April 2025 in “Archives of Dermatological Research” The combination of finasteride and minoxidil is as safe and effective as minoxidil alone for improving hair growth in men.
6 citations
,
August 2020 in “International Research Journal on Advanced Science Hub” The niosomal gel effectively delivers testosterone through the skin with fewer side effects.
3 citations
,
September 2022 in “Journal of Drug Delivery Science and Technology” Minoxidil, a hair loss treatment, works better and has fewer side effects when put into tiny particles called transethosomes, especially those containing oleic acid.
January 2026 in “Drug Delivery and Translational Research” Multicomponent crystals in microneedles improve drug delivery for hair loss treatment.
31 citations
,
December 2016 in “Anais Brasileiros de Dermatologia” DHEA reduction may be linked to frontal fibrosing alopecia, but more research is needed.