85 citations
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June 2015 in “Scientific Reports” The study found that diseases can be grouped by symptoms and that the accuracy of predicting disease-related genes varies with the data source.
82 citations
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May 2010 in “PLoS neglected tropical diseases” Secondary syphilis in Cali, Colombia, shows high Treponema pallidum presence and challenges in early diagnosis, needing better public health strategies.
76 citations
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November 2009 in “Medical Clinics of North America” Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
73 citations
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January 2013 in “European journal of dermatology/EJD. European journal of dermatology” Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.
72 citations
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March 2023 in “Biomolecules” Dupilumab effectively treats various inflammatory skin diseases beyond its initial use for atopic dermatitis.
71 citations
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January 2015 in “The Scientific World Journal” Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.
71 citations
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November 2013 in “Clinics in Dermatology” Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.
70 citations
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September 2008 in “PubMed” MicroRNAs are important for skin development and diseases and could be used for treatment and diagnosis.
69 citations
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January 2015 in “Cell & tissue research/Cell and tissue research” Keratin mutations cause skin diseases and could lead to new treatments.
68 citations
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April 2012 in “Digestive and Liver Disease” Elental is a good long-term treatment for Crohn's disease, similar to 6-mercaptopurine but with fewer side effects.
67 citations
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January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology” Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
66 citations
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September 2008 in “The Journal of Dermatology” Gastrointestinal issues are important risk factors for sebaceous gland diseases in Han adolescents.
65 citations
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September 2010 in “Journal of the Neurological Sciences” Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.
62 citations
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October 2018 in “Journal of pathology” Keratin 17 is linked to various diseases, including cancer and skin conditions, and may be a target for diagnosis and treatment.
61 citations
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October 2010 in “Postgraduate Medical Journal” Most patients with chronic kidney disease have skin problems, which get worse as the disease progresses, and dialysis doesn't greatly reduce these issues.
60 citations
,
September 2023 in “Science” BTNL proteins help control inflammatory bowel disease by maintaining specific immune cells.
58 citations
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April 2012 in “Journal of the American Academy of Dermatology” Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.
58 citations
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October 2001 in “Dermatologic Clinics” Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.
56 citations
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June 2001 in “European journal of cardiovascular prevention & rehabilitation” Early balding linked to higher heart disease risk.
52 citations
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January 2021 in “Journal of Thoracic Oncology” Effective vaccines and treatments are crucial for long-term COVID-19 control.
50 citations
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May 2021 in “Frontiers in immunology” Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.
48 citations
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January 2015 in “Indian Journal of Dermatology, Venereology and Leprology” Vitamin D is important for skin health and can help treat psoriasis, atopic dermatitis, and vitiligo.
48 citations
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October 2014 in “International Journal of Cardiology” People with alopecia are at higher risk for heart disease and have more heart-related risk factors.
47 citations
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March 2017 in “Clinical, cosmetic and investigational dermatology” Certain skin conditions may indicate or increase the risk of Parkinson's disease.
46 citations
,
November 1997 in “Journal of Neural Transmission” Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.
45 citations
,
June 2012 in “JRSM Cardiovascular Disease” Young Indians with coronary artery disease often have risk factors like smoking and central obesity, and cutaneous markers should be monitored for lifestyle changes.
41 citations
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May 2020 in “Frontiers in immunology” Hidradenitis suppurativa might be a type of autoinflammatory skin disease.
41 citations
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July 2018 in “Frontiers in Neurology” Myotonic dystrophy may be classified as a segmental progeroid disorder.
41 citations
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January 2012 in “Journal of Korean Medical Science” Over 60% of Korean military personnel had skin diseases, commonly acne and athlete's foot, linked to service length and stress.
40 citations
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November 2019 in “Frontiers in Endocrinology” Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.