research Recent advances on the mechanisms of kidney stone formation (Review)
Kidney stones form due to factors like urine concentration, calcium deposits, hormones, gut bacteria, and immune response.
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research A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features
Genetic factors influence hair traits like shape, color, and greying in Latin Americans.
research The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling
Cathepsin L is essential for normal hair growth and development.
research In vitro and in vivo evaluation of biologically synthesized silver nanoparticles for topical applications: effect of surface coating and loading into hydrogels
Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.
research Polysaccharides from Traditional Chinese Medicines: Extraction, Purification, Modification, and Biological Activity
Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.
research Transcutaneous implantation of valproic acid-encapsulated dissolving microneedles induces hair regrowth
Tiny needles with valproic acid can effectively regrow hair.
research Attempted construction of minoxidil: carboxylic acid cocrystals; 7 salts and 1 cocrystal resulted
Made 8 minoxidil samples; 1 cocrystal, 7 salts formed.
research Bioinspired tuning of glycol chitosan for 3D cell culture
Glycol chitosan hydrogels enable quick, safe 3D cell spheroid formation for various applications.
research Nanocrystals of medium soluble actives—Novel concept for improved dermal delivery and production strategy
Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.
research Transcutol containing vesicles for topical delivery of minoxidil
Transcutol-containing vesicles improve minoxidil's skin penetration and hair growth promotion.
research Jojoba Oil: An Updated Comprehensive Review on Chemistry, Pharmaceutical Uses, and Toxicity
Jojoba oil is highly valued for its diverse medicinal and industrial uses.
research Optimization of Ultrasonic-Assisted Extraction of Total Saponins fromEclipta prostrastaL. Using Response Surface Methodology
The best way to extract saponins from Eclipta prostrasta is using 70% ethanol, at 70°C for 3 hours with a 14:1 liquid to solid ratio.
research Perifollicular Fibrosis: Pathogenetic Role in Androgenetic Alopecia
Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.
research Investigation of human hair fibers using lateral force microscopy
Hair treatments like bleaching increase friction by exposing tiny pores on the hair surface.
research Rhythmic expression of circadian clock genes in human leukocytes and beard hair follicle cells
Human leukocytes and beard hair follicle cells have internal daily clocks, and PER1 and PER3 genes may indicate individual circadian rhythms.
research Human hair keratins promote the regeneration of peripheral nerves in a rat sciatic nerve crush model
Human hair keratin helps repair nerve damage in rats.
research Development of a Two-Dimensional Model for Predicting Transdermal Permeation with the Follicular Pathway: Demonstration with a Caffeine Study
Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.
research Transdermal finasteride delivery via powder-carrying microneedles with a diffusion enhancer to treat androgenetic alopecia
Microneedles with enhancer effectively promote hair growth and increase hair density.
research Transdermal film-loaded finasteride microplates to enhance drug skin permeation: Two-step optimization study
Optimized film improves finasteride skin absorption and treatment efficiency.
research Topical Minoxidil in the Treatment of Male Erectile Dysfunction
Topical minoxidil not effective for erectile dysfunction treatment.
research Micro-segmental hair analysis: detailed procedures and applications in forensic toxicology
Micro-segmental hair analysis helps detect drug use patterns and estimate drug consumption days.
research Oleic Acid Nanovesicles of Minoxidil for Enhanced Follicular Delivery
Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.
research Deoxycholic acid in the submental fat reduction: A review of properties, adverse effects, and complications
Deoxycholic acid is effective for reducing chin fat but can cause side effects and serious complications, so careful patient evaluation is needed.
research In vivo hair growth-promoting efficacies of herbal extracts and their cubosomal suspensions
Some herbal extracts, especially when used in cubosomal suspensions, were as effective as Minoxidil in promoting hair growth.
research Targeted delivery of a poorly water-soluble compound to hair follicles using polymeric nanoparticle suspensions
Nanoparticles effectively deliver water-insoluble drugs to hair follicles, stimulating hair growth without irritating the skin.
research Recent Formulation Advances of Mangiferin
Improved delivery methods can enhance mangiferin's effectiveness as a health supplement.
research Finasteride nano-transferosomal gel formula for management of androgenetic alopecia: ex vivo investigational approach
NTF gel improves finasteride delivery for hair loss treatment, reducing side effects.
research Enhancement of percutaneous absorption of Finasteride by cosolvents, cosurfactant and surfactants
Transcutol P best increases Finasteride absorption for hair loss treatment.
research Applications of steroid drugs entrapped in cyclodextrins
Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.
research Fabrication of polyvinyl pyrrolidone-K90/Eudragit RL100-based dissolving microneedle patches loaded with alpha-arbutin and resveratrol for skin depigmentation
Microneedle patches with alpha-arbutin and resveratrol can effectively reduce skin pigmentation without irritation.