November 2025 in “Journal of Investigative Dermatology” Certain CD8+ T cells attack hair follicles in alopecia areata, suggesting they could be targeted for treatment.
55 citations
,
February 2013 in “The Anatomical Record” Mouse nails are similar to human nails, making them useful for studying nail diseases.
15 citations
,
June 2015 in “PLoS ONE” Thymosin beta-4 promotes hair growth in mice.
April 2018 in “Journal of Investigative Dermatology” The keratin network in mouse skin changes during cornification and affects the skin's protective barrier.
36 citations
,
July 2004 in “Apmis” Fluorescent proteins in mouse models effectively visualize tumor blood vessel growth.
January 2000 in “The Mouseion at the JAXlibrary (Jackson Laboratory)” The lanceolate hair-J mutation in mice helps understand human hair disorders like Netherton's syndrome.
5 citations
,
July 2022 in “Radiation Research” The mouse model helps study and develop treatments for radiation-induced saliva reduction.
29 citations
,
October 2004 in “Differentiation” Multiple mouse desmoglein 1 isoforms have distinct roles in skin and hair development.
12 citations
,
January 1987 in “Carcinogenesis” TCDD changes skin cell growth and keratin production in mice.
75 citations
,
October 2012 in “Journal of Investigative Dermatology” Alopecia areata can be triggered by specific immune cells without genetic or environmental factors.
2 citations
,
June 2023 in “Journal of cell science” Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.
7 citations
,
November 2014 in “Histochemistry and Cell Biology” The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.
14 citations
,
February 2022 in “The Journal of clinical investigation/The journal of clinical investigation” Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.
31 citations
,
April 2007 in “Experimental Dermatology” Stress in mice delays hair growth and treatments blocking substance P can partly reverse this effect.
37 citations
,
January 2010 in “Human Molecular Genetics” FTase and GGTase-I are essential for skin keratinocyte health.
The curly mutation in SELH/Bc mice affects hair and may help study human genetic disorders.
48 citations
,
July 1988 in “PubMed” Rhino mice show significant meibomian gland changes, making them a potential model for studying gland disorders.
25 citations
,
October 1984 in “Journal of Clinical Investigation” The model using human skin on mice helps study human sebaceous glands.
32 citations
,
April 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Loss of keratin K2 causes skin problems and inflammation.
47 citations
,
June 2013 in “Biology of blood and marrow transplantation” Mice with human fetal thymic tissue and stem cells developed symptoms similar to chronic graft-versus-host disease.
231 citations
,
July 2008 in “Nutrition reviews” Diet changes can protect against harmful environmental effects on fetal development.
1 citations
,
December 2024 in “The Journal of Dermatology” The study developed mouse models to help research and treat hair and sweat gland issues.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Tet1/2/3 enzymes affect hair follicle cell development by influencing BMP signaling.
April 2016 in “Journal of Investigative Dermatology” Mice without the p21 gene can fully regenerate injured ears due to reduced Sdf1 increase and leukocyte recruitment, suggesting new ways to induce tissue regeneration in mammals.
233 citations
,
July 1997 in “PubMed” High levels of ornithine decarboxylase can cause tumors in mouse skin.
CaBP1 and CaBP2 are important for maintaining hearing by supporting continuous calcium currents and nerve signaling in the ear.
141 citations
,
May 2007 in “Cancer Research” CD34 is crucial for skin tumor development in mice.
October 2024 in “Journal of the Endocrine Society” Gender-affirming hormone therapy affects metabolism differently based on treatment type.
January 2004 in “Molecular biotechnology” 29 citations
,
January 2003 in “Genomics” A new mouse mutation causes skin and hair issues, influenced by another gene.