Trichotillomania treatment is improving with new therapies, but challenges like stigma and lack of training remain.
Trichotillomania involves hair-pulling due to brain and genetic factors, with behavior therapy and new drugs showing promise, but challenges like stigma and underdiagnosis persist.
Trichotillomania treatment is improving with behavior therapy and new drug approaches, but challenges like stigma and underdiagnosis remain.
May 2023 in “Cytotherapy” Hair follicle and adipose cell vesicles both protect neurons and reduce inflammation similarly.
January 2017 in “Corpus Université Laval (Université Laval)” Dutasteride may protect brain cells in early Parkinson's, while progesterone helps neuron recovery.
52 citations
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April 2002 in “Brain Research” Lower allopregnanolone levels increase stress-related dopamine release in the brain.
8 citations
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November 2019 in “Journal of Trace Elements in Medicine and Biology” Higher hair iron levels are linked to changes in brain structure and function.
1 citations
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January 2007 in “Griffith Research Online (Griffith University, Queensland, Australia)” Adult rat olfactory mucosa has stem cells that can self-renew and become different cell types.
October 2015 in “Elsevier eBooks” Pramipexole can cause side effects like dizziness, sleepiness, hallucinations, and low blood pressure, and it's important to educate patients and keep doses low.
Delta-opioid receptors affect skin cell circadian rhythms, possibly impacting wound healing and cancer.
3 citations
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September 1980 in “Experientia” Dobutamine does not mimic dopamine at therapeutic doses but may at very high concentrations; microfilaments, not microtubules, are important for wound healing in Xenopus embryos.
140 citations
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February 2014 in “Neuron” Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.
May 2024 in “Regenerative Therapy” Dendrobium officinale polysaccharide helps hair growth by activating the WNT signaling pathway.
1 citations
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June 2021 in “Biomolecules & Therapeutics” Activating δ-opioid receptors can help hair grow.
April 2019 in “Journal of Investigative Dermatology” Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.
14 citations
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June 2022 in “Neuroscience”
7 citations
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June 2011 in “Movement Disorders” A specific gene mutation is linked to a hereditary form of dystonia that responds well to certain medications.
April 2023 in “Journal of Investigative Dermatology” PRP can improve hair growth in people with hair loss, but more research is needed.
70 citations
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December 2004 in “Proceedings of the National Academy of Sciences” BMP signaling affects hair color by interacting with the MC-1R pathway.
14 citations
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April 2005 in “Experimental Dermatology” Stressed fibroblasts greatly increase melanin production in hair, skin, and eye cells, mainly due to a growth factor called bFGF.
October 2019 in “Asian College of Neuropsychopharmacology” 91 citations
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May 2003 in “PubMed” Neuroactive steroids affect cocaine's rewarding effects through the sigma1 receptor.
21 citations
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March 2002 in “Neurology” Dopamine agonists like pramipexole and ropinirole can cause reversible hair loss.
February 2026 in “Advanced Science” TTNPB helps turn stem cells into neural stem cells, improving depression-like behaviors in rats.
27 citations
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June 2023 in “Nature” Senescent melanocytes can boost hair growth by activating hair stem cells.
1 citations
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December 2024 in “Journal of Orthopaedic Research®” Aromoline and DRD4 are potential targets for osteoarthritis treatment.
April 2016 in “Journal of Investigative Dermatology” Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.
August 1994 in “Molecular Endocrinology” Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.
59 citations
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April 2016 in “Cell Reports” EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
Polydopamine is promising for personalized medicine and biomedical technology due to its strong adhesion and biocompatibility.