1 citations
,
April 2018 in “Journal of Investigative Dermatology” PRC1 is essential for proper skin development and stem cell formation by controlling gene activity.
September 2022 in “Institutional Repositories DataBase (IRDB)”
June 2021 in “Experimental and Therapeutic Medicine” MEF/KSF-conditioned medium effectively grows mouse hair follicle stem cells with bone-forming potential.
April 2018 in “Journal of Investigative Dermatology” BMP signaling is important for skin color, affecting melanin production, pigment spread, and cell movement.
September 2017 in “Journal of Investigative Dermatology” Aging causes sweat glands to shrink and move upward, leading to less elastic skin and more wrinkles.
September 2017 in “Journal of Investigative Dermatology” Aging causes sweat glands to shrink, leading to skin issues, and blue light can help hair grow.
February 2008 in “Medical & surgical dermatology” Some treatments like topical oxygen and stem cells show promise for wound healing and hair growth, but evidence for modern dressings over traditional ones is limited.
September 2017 in “Journal of Investigative Dermatology” BMPs are crucial for hair growth and their decrease by androgens leads to hair loss.
113 citations
,
November 2017 in “Scientific Reports” Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
205 citations
,
March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
137 citations
,
September 2005 in “Proceedings of the National Academy of Sciences of the United States of America” The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.
106 citations
,
September 2010 in “Stem cells” Skin-derived precursors in hair follicles come from different origins but function similarly.
85 citations
,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
76 citations
,
July 2019 in “Cellular and Molecular Life Sciences” Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.
68 citations
,
November 2012 in “Journal of Investigative Dermatology” Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.
66 citations
,
May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
56 citations
,
May 2017 in “Nature Cell Biology” Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
54 citations
,
October 2023 in “Oncogene” p63 is essential for controlling epithelial stem cells and tissue health.
54 citations
,
April 2020 in “Experimental & Molecular Medicine” Cox-2 significantly contributes to the development and progression of skin and esophageal cancers.
46 citations
,
June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
39 citations
,
January 2008 in “Journal of Endocrinology” SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.
34 citations
,
April 2018 in “EMBO journal” The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
34 citations
,
November 2010 in “Development” Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
34 citations
,
June 2008 in “In vitro cellular & developmental biology. Animal” Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.
30 citations
,
December 2017 in “Advanced Healthcare Materials” Nanoencapsulation creates adjustable cell clusters for hair growth.
28 citations
,
January 2008 in “Journal of medical investigation” Sp6 promotes tooth development by reducing follistatin levels.
26 citations
,
February 2002 in “Urologic clinics of North America” The document concludes that it's important to understand the placebo effect when evaluating the effectiveness of treatments in medical trials.
25 citations
,
October 2020 in “Journal of Racial and Ethnic Health Disparities” COVID-19 affected Black communities more in Oakland County, MI, but didn't increase death rates.
25 citations
,
August 2010 in “Journal of Biological Chemistry” Nuclear Factor I-C is important for controlling hair growth by affecting the TGF-β1 pathway.
19 citations
,
August 1999 in “European journal of endocrinology” The study concluded that testing hormone levels after stimulation is not reliable for identifying carriers of 21-hydroxylase deficiency; genetic testing is necessary.