research Dissolving microneedle array patches containing mesoporous silica nanoparticles of different pore sizes as a tunable sustained release platform
Dissolving microneedle patches can effectively deliver drugs over time.
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research Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal and Prostate Cancer
Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
research Signaling pathways in the mechanisms of drug action
Signaling pathways are key targets for developing effective drugs.
research Determination of Illegally Added Minoxidil in Herbal Hair Growth Cosmetics by HPLC
The method accurately detects illegal minoxidil in herbal hair products.
research Smart Responsive Microneedles for Controlled Drug Delivery
Smart microneedles can deliver drugs painlessly and accurately for diseases like diabetes and tumors.
research Extracellular Vesicles as Surrogates for Drug Metabolism and Clearance: Promise vs. Reality
Extracellular vesicles could help tailor drug treatments, but more research is needed.
research Determination of finasteride in anti-calvous hair cosmetics by high performance liquid chromatography
A reliable method was developed to measure finasteride in hair products.
research Nanocrystal Formation: Decoding Nucleation, Growth Mechanisms, and Advanced Drug Delivery Applications
Nanocrystals improve drug delivery and effectiveness.
research UV Spectrophotometric Stability Indicating Method Development and Validation for the Determination of Finasteride Bulk and Dosage Form.
The method accurately measures finasteride in bulk and dosage forms.
research An Innovative Reverse-Phase High-Performance Liquid Chromatography Technique For Measuring Finasteride And Tadalafil In Raw Materials And Pharmaceutical Products With Stability Indication
research Generation of comparative pharmacophoric model for steroidal 5α-reductase I and II inhibitors: A 3D-QSAR study on 6-azasteroids
The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.
research Impact of Reporter Type on Signal Detection of Cancer Therapy-Induced Alopecia: A Hypothesis-Generating Study Using the FDA Adverse Event Reporting System
Reporter characteristics affect detection of hair loss from cancer therapy.
research Selective and rapid determination of tadalafil and finasteride using solid phase extraction by high performance liquid chromatography and tandem mass spectrometry
Quick, selective detection of tadalafil and finasteride in human plasma developed.
research Formulation development of drug nanocrystals and nanoparticles for dermal delivery
Nanocrystals and nanoparticles can enhance drug delivery for skin applications by improving solubility and dissolution rates.
research Skin toxicity determined in vitro by three-dimensional, native-state histoculture.
This model can replace animal testing for quick, cost-effective skin toxicity tests.
research Dose–hair concentration relationship and pigmentation effects in patients on low-dose clozapine
Clozapine levels in hair reflect dosage and bind more to pigmented hair.
research Optimized skin optical clearing for optical coherence tomography monitoring of encapsulated drug delivery through the hair follicles
A PEG-400/oleic acid mixture best improves drug delivery monitoring through hair follicles.
research Synchronous fluorescence as a green and selective method for the simultaneous determination of finasteride and tadalafil in dosage form and spiked human plasma
A new green method accurately measures finasteride and tadalafil in drugs and plasma.
research Development of an aequorin-based assay for the screening of corticotropin-releasing factor receptor antagonists
The new assay can help develop products for hair re-growth.
research Penetration and Distribution in Human Skin Focusing on the Hair Follicle
Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
research Discussion of “A hybrid phase I‐II/III clinical trial design allowing dose re‐optimization in phase III” by Andrew G. Chapple and Peter F. Thall
The new clinical trial design is promising but needs real-world trials to test its effectiveness and possible enhancements.
research Cardiac biopsy in myocarditis
Some people have a genetic variation that makes them less effective at breaking down drugs.
research Fentanyl in hair. Chemical factors involved in accumulation and retention of fentanyl in hair after external exposure or in vivo deposition.
Fentanyl accumulates differently in hair from internal use compared to external exposure.
research Lifestyle drugs: concept and impact on society
Lifestyle drugs are mainly used by wealthy people in India but could spread to others, affecting society and youth.
research Improvement of dermal and transdermal therapies by nanocarrier-based drug delivery
Nanocarriers can improve skin treatments by effectively delivering drugs and enhancing skin hydration.
research Investigation of transfollicular caffeine penetration using microdialysis on ex vivo porcine ear skin
Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.
research MICRONEEDLE: AN OVERVIEW
Microneedles offer a painless way to deliver drugs effectively but need more research before they can be widely used.
research Development and validation of new uv-visible spectrophotometric method for the estimation of minoxidil in bulk and pharmaceutical dosage form
A new accurate and cost-effective method was developed to measure Minoxidil in different forms.
research Comparison of Efficacy and Specificity in Cancer‐Targeting Prodrug Conjugates
The document concludes that biotin, folate, and RGD peptides are promising for targeting cancer cells with prodrugs, but the conjugates are not yet tested for use.