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Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Targeting NETs may help reduce fibrosis in Crohn's disease.

Human hair keratins can be turned into useful 3D biomedical scaffolds through a freeze-thaw process.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Human hair keratins can self-assemble and support cell growth, useful for biomedical applications.

The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

Adipose tissue changes in obesity can trigger stress in fat cells.

Researchers developed a method to identify animal fibers in textiles, which works on processed and blended materials.

Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.

Microfibrils are key for permanent waves, and hydrolyzed keratin improves wave formation and hair condition.

Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.

Low humidity changes skin gene expression, but emollients can help manage these changes.

Menopause-related skin changes may increase fungal infections and inflammation.

Silver nanoparticles made from Dracaena trifasciata extracts have strong antioxidant properties.

Dorper sheep's wool shedding is linked to specific genes and pathways, which may help understand human hair growth.

Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.

Researchers found that certain RNA sequences play a role in yak hair growth and these sequences are somewhat similar to those in cashmere goats.

Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.

PEGylated liposomal doxorubicin improves cancer treatment effectiveness and reduces side effects like heart damage and hair loss.

Topical immunotherapy with DPCP is most effective for certain alopecia areata types, with success linked to age and disease duration, and influenced by a gene polymorphism.

Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.

Trichothiodystrophy is a rare genetic disorder causing hair issues and sometimes linked to DNA repair defects.

TTD patients don't have a higher skin cancer risk because their main issue is with transcription, not DNA repair.

A new classification for trichothiodystrophy helps identify genetic causes and potential treatments.

Specific brain and bone imaging findings can help diagnose Trichothiodystrophy.

Trichothiodystrophy hair is structurally abnormal with protein and organization issues.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.