research The Risks and Benefits of 5α-Reductase Inhibitors for Prostate-Cancer Prevention
5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.
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930-960 / 1000+ results research Role of Androgen in Mesenchymal Epithelial Interactions in Human Hair Follicle
Androgens promote beard growth but cause hair loss in androgenetic alopecia, with TGF-β1 as a potential treatment target.
research Dutasteride
Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.
research Activation of AR Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation
Breast cancer treatments work better with AR activation, improving results and reducing side effects.
research Pathologic Quiz Case: A 69-Year-Old Man With a Brown-Black Facial Papule
A rare benign skin growth called melanocytic matricoma was identified in a 69-year-old man.
research Soil, grain and water chemistry and human selenium imbalances in Enshi district, Hubei Province, China
Selenium levels in Enshi District need careful monitoring to prevent health issues.
research Mitochondrial-related genes as prognostic and metastatic markers in breast cancer: insights from comprehensive analysis and clinical models
Mitochondrial genes help predict breast cancer outcomes and spread.
research Inhibition of the CoREST Repressor Complex Promotes Wound Re-Epithelialization through the Regulation of Keratinocyte Migration
Corin speeds up wound healing by helping skin cells move and grow.
research Complete remission of alopecia areata under treatment of chronic hand eczema with alitretinoin
Alitretinoin may help treat alopecia areata.
research The role of Atg5 gene in tumorigenesis under autophagy deficiency conditions
Atg5 can promote tumors when autophagy is deficient but suppresses them under normal conditions.
research Something From Nothing: Seeking a Sense of Self
Communication shapes our sense of self.
research ApoBDs: a paradigm shift from cellular debris to therapeutic vehicles
ApoBDs, once seen as waste, are now viewed as potential tools for disease treatment and tissue repair.
research Learning and Friendship
The author found the Dermatology Nurses’ Association’s annual meeting valuable for both learning and making friends.
research Outer root sheath cells secrete oxytocin for hair growth promotion and stem cell proliferation
Oxytocin from hair cells helps hair growth and stem cell increase.
research Pediatric Clinical Trial Program in Progress: A Phase 3 Study and Long-term Extension Study to Evaluate the Efficacy and Safety of Ritlecitinib in Children 6 to <12 years of Age With Severe Alopecia Areata
Ritlecitinib is being tested for safety and effectiveness in young children with severe alopecia areata.
research Engineered Exosomes Co-Delivering EGF and FGF Ameliorate Androgenetic Alopecia in a Mouse Model
Engineered exosomes with EGF and FGF improve hair growth in mice with hair loss.
research Bifunctional sodium hyaluronate microneedle patches integrating 5α-reductase and ROS regulation for boosted hair regeneration
The microneedle patch boosts hair growth by reducing DHT and oxidative stress.
research The Excesses of Cosmetic Medicine
Ethical standards are crucial in cosmetic medicine to maintain integrity.
research The study of miRNA-211 affects melanogenesis progress in Cashmere goats via suppressing AP1S2
miRNA-211 reduces melanin in Cashmere goats by suppressing AP1S2.
research Proposal Statement
Stronger regulations and protections are needed for digital platforms to ensure safety and fairness in health, education, and labor.
research 801 TEC family kinase inhibitors as a novel class of therapeutics in alopecia areata
ITK inhibitors may effectively treat alopecia areata.
research Identification and Expression of the Target Gene SLC24A2 of oar-miR-377 and Its Novel SNPs Effects on Wool Traits in Sheep
A specific genetic variation affects wool quality in sheep.
research Classification and Frequency of Crown Whirlpool Patterns in Male Hair Transplant Patients
Understanding crown whorl patterns can improve hair transplant results for men.
research Unresponsive Alopecia Areata Treated Successfully with Liquid Nitrogen Cryotherapy: A Study of Five Patients
Liquid Nitrogen Cryotherapy effectively treats unresponsive Alopecia Areata with minimal side effects.
research Topological Markers for Subcellular Chemical Mapping using TOF-SIMS
TOF-SIMS improved chemical mapping in cells, confirming gunshot residue, tracking anti-tumor drugs, and identifying molecules in mosquitoes and wounds.
research Editors' Picks
Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.
research Dutasteride: a guide to its use as monotherapy in benign prostatic hyperplasia
Dutasteride effectively treats benign prostatic hyperplasia, improving symptoms and quality of life.
research Book reviews
The reviews highlighted practical advice and insights from various psychology and therapy books.
research Mechanisms regulating skin immunity and inflammation
The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
research Adverse Health Effects of Selenium in Humans
High selenium exposure can harm thyroid function, immune system, liver, skin, and may increase neurotoxicity and cancer risk.