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Loss of Dnmt3a and Dnmt3b leads to more aggressive skin tumors, but blocking PPAR-γ can reduce this effect.

A potential treatment for atopic dermatitis could be to increase PADI1 expression to improve skin barrier function.

HOXC13 is essential for hair and nail development by regulating Foxn1.

The ND1 gene of the Asian black bear Sichuan subspecies is similar to other bear species.

MPA increases cancer spread by boosting Eph A2 activity.

Mutations in the DSG4 gene cause fragile, sparse hair in humans, mice, and rats.

Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.

Two new gene mutations cause a rare hair disorder.

The DiLiCre mouse model is an effective tool for precise genome editing using light.

The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.

Vitamin D receptor helps control hair growth genes in skin cells.

A new mutation in the KRT86 gene causes a hair disorder with variable expression.

The STRIPAK complex is crucial for skin cell organization and creating a functional skin barrier.

The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.

Sostdc1 controls the size and number of hair and mammary gland structures.

miR-195-5p reduces hair growth ability in cells by blocking a specific growth signal.

Targeting the TNFRSF1B gene may help treat hair loss.

A mutation in the VDR gene affects hair cycling without needing ligand binding.

The P133R mutation in AKR1D1 enzyme causes harmful bile acid buildup, explaining related health issues.

A new mutation in the K6b gene caused a girl's late-appearing nail condition.

High levels of ODC and a mutant Ha-ras gene cause tumors in mice.

The AR gene is linked to male-pattern baldness, TNFSF4 to heart disease, SLC19A3 to BBGD, MCT8 to a syndrome, and segmental duplications to genetic variation.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Mutations in the desmoplakin gene can cause hair problems and deadly heart disease.

Cathepsin L deficiency causes hair and skin issues in mice.

The Foxn1(-/-) phenotype disrupts hair growth and affects skin stem cells.

DS-2325a is safe and well-tolerated, supporting further development for Netherton Syndrome treatment.

Upadacitinib effectively treats pyoderma gangrenosum.

A new mutation in the Connexin 26 gene was found in a patient with KID syndrome, expanding the known disorders linked to this gene.