2 citations
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October 2023 in “Biology” Cobalt is important for health but too much or too little can cause health problems, and its environmental buildup is a concern.
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September 2021 in “BioEssays” Dandruff might be caused by changes in how hair follicles naturally release oils and an immune response to this imbalance.
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June 2002 in “Molecular Biology of the Cell” Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.
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June 2020 in “Pharmaceutics” New nanocarriers improve drug delivery for disease treatment.
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February 2005 in “Journal of the American Academy of Dermatology” Focal palmoplantar callosities may help diagnose non-Herlitz junctional epidermolysis bullosa.
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December 2012 in “Current opinion in cell biology” Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
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July 1994 in “Journal of Dermatological Science” Keratin mutations may cause scarring alopecia by damaging hair structure.
April 2024 in “MGM Journal of Medical Sciences” Traditional Indian home remedies are effective and culturally important.
66 citations
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May 2002 in “The Plant Journal” The IRE gene is important for normal root hair growth in Arabidopsis plants.
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April 1970 in “Biochemical pharmacology” Stilbamidine and hydroxystilbamidine inhibit enzyme release from lysosomes and have effects similar to cortisol and chloroquine.
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September 2024 in “International Journal of Molecular Sciences” Polymers can be designed to mimic natural cell environments for medical uses.
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November 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.
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January 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” A faulty KLHL24 gene leads to hair loss by damaging hair follicle stem cells.
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May 2019 in “Frontiers in Cell and Developmental Biology” Abnormal ECM and immune cell interactions can cause skin diseases.
Seborrheic dermatitis and dandruff are often treated with antifungal and anti-inflammatory medications, which can reduce symptoms and yeast growth on the scalp.
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October 1998 in “Genomics” Mouse keratin 6 genes evolved independently from human ones and are regulated differently.
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October 2007 in “Molecular Therapy” Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.
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December 1998 in “Journal of Biological Chemistry” Keratin 19 forms less stable and shorter filaments than keratin 14, giving unique traits to certain skin cells.
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May 2014 in “Journal of Biological Chemistry” A chimeric keratin partially improved skin structure in mice lacking keratin 5, but didn't fully restore normal skin.
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May 2012 in “Genesis” Bmpr2 and Acvr2a receptors are crucial for hair retention and color.
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November 1998 in “Journal of dermatological science” Knocking out certain genes in mice helps understand skin and hair growth problems.
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April 2023 in “Animals” Deleting the EDAR gene in Cashmere goats affects genes and proteins related to hair growth.
188 citations
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December 2020 in “Foods” Polyphenols in plant foods help prevent diseases and have potential uses in food, cosmetics, and more.
119 citations
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September 2000 in “Journal of Biological Chemistry” GKLF/KLF4 and Sp1 control Keratin 19 gene activity, influencing cancer-related changes.
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November 2020 in “International journal of biochemistry & cell biology” Keratin proteins are essential for keeping the cells in the human colon healthy and stable.
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August 2024 in “Journal of Investigative Dermatology” In vitro skin models are improving but still need more innovation to fully replicate human skin.
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June 2024 in “Pharmaceutics” Nanoformulations improve drug delivery through the skin, reducing side effects and enhancing effectiveness.
30 citations
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February 2022 in “Pharmaceutics” 3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.
25 citations
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February 2024 in “Pharmaceutics” Nanocarriers can make acne treatments more effective and gentle on the skin.