45 citations
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November 2012 The conclusion is that androgen receptor gene polymorphism might be a marker for polycystic ovary syndrome, but more research is needed.
33 citations
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January 2000 in “Acta Oto-Laryngologica” Epidermal growth factor increases extra hair cells in newborn rat ears.
Diagnosing oral ulcers can be complex and requires careful examination and follow-up.
April 2026 in “Amino Acids” Polyamines are crucial for skin tumor development, and inhibiting them can prevent tumors.
17 citations
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September 2014 in “PLoS ONE” SK2 channels help control sensory signals in rat muscle spindles and hair follicles.
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January 2023 in “Journal of Clinical Investigation” Specific mutations in a receptor cause facial abnormalities and hair loss.
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October 2013 in “Endocrine” Blood tests can detect ovarian Leydig cell tumors when scans don't, and surgery can confirm and treat these tumors.
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December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
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June 2010 in “Experimental Dermatology” Lower MC2R expression may contribute to alopecia areata.
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August 2015 in “Experimental Dermatology” The mineralocorticoid receptor temporarily affects mouse skin development, but the glucocorticoid receptor has a more lasting impact.
28 citations
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January 2009 in “Journal of Investigative Dermatology” Stem cells in eccrine glands could be used for regenerative medicine.
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December 2020 in “The FASEB Journal” Blocking adenosine A2B receptor may prevent or treat hearing loss.
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August 2023 in “Developmental Cell” Mechanosensory neurons adapt to different skin types after birth.
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January 1995 in “Archives of dermatological research” OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.
Suppressing ODC activity reduces tumor growth in hair follicles.
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
February 2025 in “International Journal of Molecular Sciences” RORA plays a key role in controlling seasonal hair molting by affecting hair follicle cell activity.
286 citations
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April 2009 in “The journal of neuroscience/The Journal of neuroscience” TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.
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April 2015 in “Experimental Dermatology” Certain genes controlled by OVOL1 are crucial for creating new hair follicles.
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February 2009 in “Journal of Neuroscience” Pregnancy increases certain GABAA receptors in rat brains, influenced by steroid levels.
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August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Certain cells in the adult mouse ear come from cranial neural crest cells, but muscle and hair cells do not.
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May 1997 in “Journal of Dermatological Science” Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.
11 citations
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September 2016 in “Journal of virological methods” Rabies virus was found in specific skin cells of rabid dogs' muzzles, suggesting these cells could help diagnose rabies.
July 2024 in “Journal of Investigative Dermatology” Human hair follicles have their own thyroid hormone system.
PCOS involves genetic and immune factors, especially T cells, affecting its development.
15 citations
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August 2019 in “F1000Research” CMG2 and TEM8 receptors have distinct roles in skin and growth disorders, affecting collagen breakdown and growth.
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June 2012 in “Molecular Biology Reports” VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.
July 2025 in “Reproductive Biology and Endocrinology” Early androgen exposure affects hormone receptor expression in adult female rats' brains, but not in males.
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January 1985 in “Dermatology” Higher levels of certain immune cells in hair follicles may contribute to alopecia areata.