75 citations
,
January 2004 in “Molecular and Cellular Biology” XEDAR deficiency prevents muscle degeneration in EDA-A2 transgenic mice.
February 2024 in “Recima21” Covid-19 can cause hair loss due to immune and psychological factors.
4 citations
,
July 2020 in “Biochemical and Biophysical Research Communications” A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.
76 citations
,
May 2011 in “Cell death and differentiation” A20 protein is crucial for normal skin and hair development.
249 citations
,
May 2003 in “Developmental Biology” Ectodysplasin-A1 is crucial for developing hair, teeth, and glands.
17 citations
,
August 2012 in “Journal of Medical Genetics” A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.
January 2012 in “Journal of Northwest A & F University” The Eda gene helps regulate the hair cycle in goats.
April 2012 in “Encyclopedia of Life Sciences” Different genes are linked to various types of hair loss.
133 citations
,
February 2019 in “PLoS Biology” Feather patterns in birds are shaped by signaling interactions and cell movements, with EDA/EDAR crucial for pattern formation.
43 citations
,
February 2013 in “Developmental dynamics” Foxi3 expression in developing teeth and hair is controlled by the ectodysplasin pathway.
A genetic mutation in the EDA gene causes hypohidrotic ectodermal dysplasia in cats.
48 citations
,
January 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Chemokine signaling is important for hair development.
Older age, obesity, hirsutism, and having children increase metabolic risk in women with PCOS.
January 2012 in “Surgical & Cosmetic Dermatology” Nutrition can improve hair strength and reduce breakage.
The extract of Guazuma ulmifolia Lam. has limited antioxidant properties and cannot prevent uric acid synthesis.
Lichen planopilaris and frontal fibrosing alopecia are likely the same disease with different clinical appearances.
Clinical signs don't match inflammation levels in lichen planopilaris and frontal fibrosing alopecia.
Laser hair removal may cause skin changes that prevent hair regrowth.
42 citations
,
April 2009 in “Human Genetics” A specific genetic mutation may increase male pattern baldness risk, especially in Europeans.
12 citations
,
December 2020 in “Archives animal breeding/Archiv für Tierzucht” EDA and EDAR are important for hair follicle development in cashmere goats and affect other related genes.
12 citations
,
January 2016 in “Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie” Researchers found a new mutation in the EDA gene that likely causes missing teeth and mild skin symptoms in one family.
1 citations
,
April 2025 in “Pediatria i Medycyna Rodzinna” Restoring EDA and WNT pathways early may help improve skin, hair, and teeth issues in hypohidrotic ectodermal dysplasia.
196 citations
,
March 2016 in “Nature Communications” Genetic factors influence hair traits like shape, color, and greying in Latin Americans.
Correcting EDA fibronectin organization and YAP translocation can improve wound healing in fibrotic conditions.
September 2025 in “Editora Pasteur eBooks” Continuous learning and personalized treatments are crucial in dermatology due to rapid technological advancements.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Immune cells are essential for early hair and skin development and healing.
March 2026 in “Calcified Tissue International” The EDA pathway plays a key role in bone development by interacting with other signaling pathways.
October 2025 in “Open Repository of the University of Porto (University of Porto)” Pharmacists play a crucial role in health literacy and patient care.
January 2024 in “Surgical & Cosmetic Dermatology” Exosomes may help treat skin diseases and improve skin rejuvenation.
November 2025 in “Open Repository of the University of Porto (University of Porto)” Continuous use of finasteride and minoxidil is effective for treating androgenetic alopecia.