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Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.

PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.

The research found that blocking a gene called NEMO can potentially prevent harmful effects of aging at the cellular level.

One type of progenitor cell can maintain normal skin in mice.

The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.

Atoh1 expression can create new Merkel cells in the skin.

Stem cells control their future role by changing ERK signal timing, affecting tissue regeneration and cancer.

IL-18 signaling helps mature Tregs move into the thymus.

Forensic DNA phenotyping can now predict more physical traits and ancestry from DNA, but further improvements are needed.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

Sex hormones affect brain cells differently in males and females.

The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.

A 5-year-old girl with a rare genetic disorder, lipoid proteinosis, showed reduced new lesions but persistent scars after avoiding skin trauma.

The FTO gene hinders stem cells in hair follicles from becoming pigment cells.

Normal skin results from interactions between EGF and the Tabby mutation.

Targeting adipocyte-to-mesenchymal transition could help treat fibrosis.

DNA phenotyping can predict physical traits like eye, hair, and skin color, improving forensic investigations.

Corticosterone makes ethanol more effective at blocking brain processes important for learning and memory.

Super-enhancers control CD25 expression in specific cell types, affecting immune function.

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

Skin cells control immune cell placement, helping the skin respond better to challenges.

Inhibiting HSP90 increases cell adaptability and survival under stress.

Scientists found a new type of skin cell that could help with skin repair and these cells work better with a certain protein.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

The hairy ear mutation in mice is linked to changes in gene expression affecting hair growth.

A TNFAIP3 gene mutation can cause unusual and varied symptoms of lupus and Sjogren's syndrome.

The study found that diseases can be grouped by symptoms and that the accuracy of predicting disease-related genes varies with the data source.

Myc changes chromatin in stem cells, causing them to leave their niche.