January 2018 in “Digital Commons - PCOM (Philadelphia College of Osteopathic Medicine)” Topical eflornithine effectively reduces unwanted facial hair in women with hirsutism for at least 6 months.
19 citations
,
October 2008 in “Expert Review of Dermatology” EGF receptor is crucial for skin health and its inhibitors can cause skin rashes.
May 2025 in “Egyptian Journal of Dermatology and Venerology” Certain gene changes and hormone levels are linked to female hair loss.
September 2023 in “Plant journal” A protein called GIS3 is important for the growth of root hairs in Arabidopsis by controlling two genes with the help of certain growth signals.
December 2020 in “Research Square (Research Square)” A genetic change in the FGF5 gene affects hair growth in cashmere goats.
1 citations
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January 2024 in “International Journal of Applied Biochemistry and Molecular Biology.” Higher EGF levels are linked to more severe alopecia areata.
November 2025 in “Biomolecules” FGF22 helps hair follicle stem cells grow and develop.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” A patient with a PLEC mutation has epidermolysis bullosa, muscular dystrophy, and myasthenia gravis, which improved with steroid treatment.
3 citations
,
February 2022 in “Journal of Dermatological Science” Early onset female hair loss is linked to lower hair density, scalp issues, and certain genetic factors.
124 citations
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December 1983 in “Developmental Biology” EGF receptors are crucial for skin cell growth and decrease with age.
Ethanol changes GABAA receptor α4 subunit levels through phosphorylation and neuroactive steroids.
15 citations
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February 2021 in “Scientific Reports” RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.
77 citations
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April 2004 in “Gene expression patterns” The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.
February 2022 in “Research Square (Research Square)” A protein made in a plant stopped hair growth in mice.
3 citations
,
August 2017 in “Clinical case reports” A rare skin condition causes red and dark patches on the face and limbs.
3 citations
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January 1984
September 2007 in “Journal of Investigative Dermatology” ANp63 is crucial for skin integrity, new filaggrin gene mutations link to eczema, hair can regrow from non-stem cells, sunburns are increasing, and glucocorticoids help treat skin allergies by affecting immune cells.
April 2023 in “Journal of Investigative Dermatology” Type 1/17 inflammation in psoriasis increases skin cell growth due to a molecule that could be a new treatment target.
September 2023 in “Journal of the American Academy of Dermatology” Oral difelikefalin significantly reduces itch in notalgia paresthetica.
mEphA1 receptor tyrosine kinase is important for skin and hair development and may play a role in certain diseases.
August 2025 in “Bioactive Materials” Ac-GFFY-IGF peptide is a promising, safe, and effective treatment for hair loss, better than current options.
29 citations
,
June 2015 in “Kidney International” Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.
10 citations
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October 2000 in “PubMed” E6/E7 oncogenes in hair follicles cause continuous hair growth by skipping the resting phase.
5 citations
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December 2023 in “Current Biology” A feedback loop between LRH and RSL4 controls root hair growth in Arabidopsis.
1 citations
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July 2016 in “Dermatologic surgery” March 2022 in “International Journal of Trichology” Erlotinib can cause unusual hair growth, like long eyelashes and facial hair.
7 citations
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November 2016 in “Oncotarget” UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.
44 citations
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January 2017 in “Journal of Investigative Dermatology” Mutations in the KLHL24 gene cause skin blistering in epidermolysis bullosa simplex.
April 2017 in “Journal of Investigative Dermatology” Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.
February 1968 in “PubMed”