research Evaluation of a novel hybrid polymer in hair treatment
The new polymer improves dyed hair's color, moisture, shine, and smoothness.
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Long-term alcohol exposure alters brain receptor function differently in various brain regions.
research Folate-cyclodextrin Conjugate for Targeted Chemotherapy
The folate-cyclodextrin conjugate targets cancer cells more precisely, potentially reducing chemotherapy side effects.
research Pharmacophore Models for Toxicology Prediction
Pharmacophore models can predict liver toxicity and central nervous system toxicity, but they have limitations and specific requirements.
research Allopregnanolone-mediated protective effects of progesterone on tributyltin-induced neuronal injury in rat hippocampal slices
Progesterone protects neurons from damage by converting to allopregnanolone, which works through GABAA receptors.
research Advancing Design Strategy of PROTACs for Cancer Therapy
PROTACs show promise for cancer treatment, but designing them effectively is challenging.
research Skin deposition and permeation of finasteridein vitro: effects of propylene glycol, ethanol and sodium lauryl sulfate
Propylene glycol and ethanol increase finasteride skin absorption, sodium lauryl sulfate doesn't.
research Mapping the accessibility of the disulfide crosslink network in the wool fiber cortex
Cysteines in wool fibers are accessible and form important disulfide bonds.
research Ectrodactyly, Ectodermal Dysplasia, and Cleft Lip/Palate Syndrome with Concomitant Lymphopenia: A Novel TP63 Mutation
A new TP63 mutation was found in a baby with EEC syndrome, showing the need for TREC testing to check for immune issues.
research Inorganic Nanozymes: Prospects for Disease Treatments and Detection Applications
Nanozymes could improve disease treatment and detection.
research Neurosteroids and Epileptogenesis
Neurosteroids may help prevent seizures and slow epilepsy progression.
research Formulation Development, Pharmacological Evaluation, and Characterization of <i>Eclipta alba</i> Phytosomes
Eclipta alba phytosomes improve bioavailability and therapeutic effects.
research Parasitic angiosperms, semagenesis and general strategies for plant–plant signaling in the rhizosphere
Reactive oxygen species are key for parasitic plant attachment and affect root development in various plants.
research Epigenetic Effects of Gender-Affirming Hormone Treatment: A Pilot Study of the ESR2 Promoter’s Methylation in AFAB People
Testosterone treatment may change estrogen receptor methylation in AFAB individuals.
research Chitosan-decorated polystyrene-b-poly(acrylic acid) polymersomes as novel carriers for topical delivery of finasteride
Chitosan-decorated carriers may improve topical finasteride delivery for hair loss treatment.
research NEMESIS - EXAMPLE OF OPEN ACCESS JOURNAL PROMOTING NEGATIVE RESULTS IN SCHOLARLY PUBLICATIONS
Nemesis journal highlights the value of negative results in science and offers free access to all.
research Neurotoxins Acting at Synaptic Sites: A Brief Review on Mechanisms and Clinical Applications
Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.
research Chemical and photo-oxidative hair damage studied by dye diffusion and electrophoresis.
Chemical treatments and light exposure damage hair proteins.
research Improving the treatment of bacterial infections caused by multidrug-resistant bacteria through drug repositioning
Using existing drugs for new purposes can effectively treat infections resistant to multiple antibiotics.
research Chronic progesterone treatment augments while dehydroepiandrosterone sulphate prevents tolerance to ethanol anxiolysis and withdrawal anxiety in rats
Progesterone increases alcohol tolerance and withdrawal anxiety, while DHEAS prevents them.
research Formulation and evaluation of self-nanoemulsifying drug delivery system for improved oral delivery of exemestane hydrochloride
The new drug delivery system improves exemestane's absorption and effectiveness.
research NEW NON SYNTHETIC MOLECULES ARE ABLE TO INHIBIT APOPTOSIS IN DERMAL PAPILLAR CELLS OF HAIR BULB
New molecules can prevent cell death in hair follicles.
research Ethosomes in hair dye products as carriers of the major compounds of black tea extracts
Ethosomes improve black tea extract absorption in hair dye.
research Crystal Structure of 3-Oxo-4-Aza-5-Alpha-Androstone-17 β-Tert-Butyl Carboxamide with an O···H–(C, N) Acceptor Four-Center Hydrogen Bond
The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.
research Novel anticonvulsive effects of progesterone in a mouse model of hippocampal electrical kindling
Progesterone can reduce seizures without relying on the GABAA receptor pathway.
research A Semi-Dissolving Microneedle Patch Incorporating TEMPO-Oxidized Bacterial Cellulose Nanofibers for Enhanced Transdermal Delivery
The patch delivers more drugs through the skin effectively.
research The occurrence of the ε-(γ-glutamyl)lysine cross-link in the medulla of hair and quill
research Different localizations of drugs simultaneously administered in a strand of hair by micro‐segmental analysis
Drugs localize differently in hair strands based on their properties.
research N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase
Scientists found new, better-working inhibitors for a hormone-related enzyme.
research Cellulose nanocrystal-stabilized Pickering emulsion gels as vehicles for follicular delivery of minoxidil
New gels using cellulose nanocrystals effectively deliver minoxidil to hair follicles, promoting hair regrowth.