122 citations
,
November 2014 in “BMC Medicine” Oral testosterone therapy raises heart risk more than other methods.
January 2022 in “World journal of pharmaceutical sciences” Many women with polycystic ovarian disease show symptoms like excessive hair growth, acne, hair loss, and have high levels of certain hormones.
November 2022 in “Journal of the Endocrine Society” A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.
5 citations
,
January 2020 in “in Vivo” Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.
136 citations
,
January 2004 in “Neuroscience” Testosterone increases seizure risk through its conversion to specific neurosteroids.
23 citations
,
July 2015 in “The Journal of Membrane Biology” Testosterone increases certain proteins in the uterus, reducing fluid volume.
9 citations
,
December 2009 in “Cancer Research” Both vaginal testosterone cream and Estring effectively manage vaginal dryness in women with early-stage breast cancer on aromatase inhibitors.
Testosterone raises blood pressure by affecting kidney function and brain gene regulation over time.
46 citations
,
July 1974 in “The Journal of Clinical Endocrinology & Metabolism” Low estrogen and high testosterone may cause excessive hair growth in women.
7 citations
,
April 2011 in “American journal of obstetrics and gynecology” A woman's virilization symptoms were caused by her partner's use of testosterone cream, which resolved after they separated.
1 citations
,
February 2016 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” An 84-year-old woman's hair loss was due to a rare condition called Leydig cell hyperplasia, which was treated with surgery.
September 2008 in “Fertility and Sterility” Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.
58 citations
,
July 1974 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Cyproterone acetate combined with ethinyl estradiol significantly reduced hirsutism in women.
April 2026 in “BMJ Case Reports” Leydig cell tumors can cause high testosterone in women and are treated by removing the ovaries.
November 2022 in “Journal of the Endocrine Society” A rare ovarian tumor caused high testosterone and excess hair in a woman, which was resolved after tumor removal.
January 2021 in “touchREVIEWS in Endocrinology” Surgery successfully treated a hidden ovarian tumor causing hair loss and excess hair growth in a postmenopausal woman.
December 2024 in “AACE Clinical Case Reports” Ovarian hyperthecosis can cause polycythemia, and surgery can normalize symptoms.
66 citations
,
October 1987 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Measuring androstanediol glucuronide in blood is useful for assessing and tracking treatment in women with excessive hair growth.
17 citations
,
April 1997 in “Archives of dermatology” The document describes a treatment for excessive hair growth in a teenage girl using medication and birth control, but does not report the results.
October 2024 in “Journal of the Endocrine Society” The case highlights the complexity of diagnosing high testosterone in older women and the need for thorough testing.
May 2023 in “Problems of Endocrinology” Men with high testosterone may have higher morning blood pressure, unlike those with high DHT.
20 citations
,
October 2017 in “Clinical Endocrinology” The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.
9 citations
,
November 2013 in “Gynecological Endocrinology” A woman had high testosterone due to an ovarian issue, which was fixed with surgery.
5 citations
,
January 2014 in “Postepy Dermatologii I Alergologii” Hormonal treatments like birth control pills can improve acne in women with excess hair growth and hormone imbalances.
February 2012 in “Reactions Weekly” A woman got male pattern baldness from touching her husband's testosterone gel.
6 citations
,
July 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” A woman had a rare liver tumor causing male-like physical changes, highlighting the need for thorough checks when such symptoms appear.
19 citations
,
March 2008 in “Nature clinical practice endocrinology & metabolism” A combined drug and laser treatment improved hirsutism in a PCOS patient, also enhancing her heart health and requiring regular liver and kidney checks.
5 citations
,
October 2014 in “Gynecological Endocrinology” Triptorelin helps evaluate hormone production in Sertoli-Leydig cell tumors.
4 citations
,
November 2018 in “Endocrinology, Diabetes & Metabolism Case Reports” GnRH analogue can help diagnose ovarian causes of high testosterone in postmenopausal women when scans don't show the cause.
3 citations
,
September 2020 in “Journal of developmental and behavioral pediatrics/Journal of developmental & behavioral pediatrics” The document discusses a young boy with autism and early puberty but does not provide a conclusion on managing his behavior.