19 citations
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October 2017 in “The FASEB Journal” Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.
5 citations
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October 2016 in “Experimental Dermatology” Activin A is important for creating new hair follicles.
November 2022 in “Research Square (Research Square)” Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.
April 2018 in “Journal of Investigative Dermatology” Activating Nrf2 helps wounds heal faster by increasing hair follicle stem cells.
44 citations
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September 2019 in “The EMBO Journal” Lymphatic vessels are essential for hair follicle growth and skin regeneration.
August 2019 in “Journal of Investigative Dermatology” Frog skin cells need the protein desmoplakin for proper development and cell layer formation.
100 citations
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September 2017 in “Molecular and Cellular Endocrinology” Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” DNA methylation controls hair follicle gene expression in cashmere goats.
160 citations
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January 2014 in “Seminars in cell & developmental biology” Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
October 2025 in “Animals” miR-200a reduces goose fibroblast growth by targeting PITX2 in the Wnt pathway.
7 citations
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January 2023 in “Frontiers in Cell and Developmental Biology” Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.
August 2022 in “Biomedicines” Turning off the Lhx2 gene in mouse embryos leads to slower wound healing and scars.
August 1994 in “Toxicology in Vitro” A lab model of human skin was created to study skin tumor promoters without using actual human skin.
5 citations
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February 2023 in “Frontiers in Veterinary Science” Ovine dermal papilla cells are promising for hair growth research due to their stable properties and hair-inducing abilities.
2 citations
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January 2023 in “Frontiers in Genetics” Overexpressing ovine β-catenin in mice skin increases hair follicle density and growth.
1 citations
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July 2007 in “Journal of Investigative Dermatology” The mutation causes hairless mice due to mislocalized and dysfunctional HR protein.
October 2022 in “Academic journal of science and technology” Stem cells, especially from fat, show promise for treating hair loss.
12 citations
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April 2019 in “Nature protocols” Scientists created a functional 3D skin system from stem cells that can be transplanted into wounds.
19 citations
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May 2016 in “Matrix Biology” Deleting a specific protein in skin cells disrupts normal hair growth and development.
10 citations
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October 2020 in “Frontiers in Cell and Developmental Biology” Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
2 citations
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January 2022 in “Journal of Investigative Dermatology” Hedgehog signaling in skin cells is crucial for hair growth and skin healing, but needs to be balanced to avoid harmful effects like scarring and cancer.
2 citations
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November 2019 in “FEBS open bio” Combining specific inducers helps dermal papilla cells regain hair-forming ability.
November 2025 in “Frontiers in Cell and Developmental Biology” The study maps goat hair follicle cells, revealing key genes and pathways involved in hair growth and cell death.
333 citations
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March 2000 in “Proceedings of the National Academy of Sciences” Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.
57 citations
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May 2016 in “Matrix Biology” Laminin α5 is essential for skin communication and health.
46 citations
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August 2006 in “Mechanisms of Development” Runx1 is crucial for proper hair structure and development.
23 citations
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March 2019 in “Gene” Editing the FGF5 gene in sheep increases wool length, confirming its role in hair growth.
14 citations
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December 2016 in “PloS one” Keratin 26 affects cashmere goat hair growth and is influenced by various treatments.
8 citations
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September 2017 in “Scientific Reports” MAD2B slows down the growth of skin cells that are important for hair development by interacting with TCF4.
7 citations
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December 2019 in “Experimental and Therapeutic Medicine” WNT10B affects hair growth by altering gene activity in hair cells.