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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.

Younger transgender women have surgery earlier, are mostly attracted to men, and show more preoperative depression that improves after surgery compared to older transgender women.

People with polycystic ovary syndrome (PCOS) are more likely to have higher levels of depression and anxiety, but their personality traits are similar to those without PCOS.

Sun-exposed skin shows different cell activity and gene expression, suggesting targets to prevent skin aging and cancer.

Removing Sprouty genes in mice causes various hormone-related issues but does not increase cancer risk by one year of age.

Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Doctors should watch for and treat hormonal issues in obese patients beyond just diabetes.

Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.

Adrenal disorders often cause high blood pressure in young people.

Skin problems in older people can indicate hormonal diseases, nutritional deficiencies, or conditions like diabetes, menopause, and HIV.

Dermatologists can help diagnose endocrine disorders like PCOS and metabolic syndrome by looking at skin symptoms.

Korean and Caucasian men with male pattern baldness have different hair steroid levels.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

Newborn skin is uniquely prepared to adapt to new environments compared to adult skin.

Differentiating PCOS from NCAH helps improve diagnosis and treatment.

Myo-inositol and D-chiro-inositol improve hormonal and physical symptoms in teenage girls with PCOS.

Electrical stimulation with a low-calorie diet reduces appetite, weight, and blood pressure in obese people with sleep apnea.

Continuous glucose monitoring and GLP-1 receptor agonists improve diabetes management, but personalized care and education are crucial.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Male-pattern baldness might be caused by the effect of hormones on scalp blood vessels.