305 citations
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March 2018 in “International journal of molecular sciences” The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.
220 citations
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March 2020 in “Advanced functional materials” Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
136 citations
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May 2019 in “Cells” Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
130 citations
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November 2017 in “Frontiers in Immunology” The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
119 citations
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March 2020 in “Frontiers in Bioengineering and Biotechnology” Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
76 citations
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February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
76 citations
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July 2019 in “Cellular and Molecular Life Sciences” Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.
70 citations
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February 2021 in “International Journal of Molecular Sciences” Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.
65 citations
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June 2021 in “Frontiers in Pharmacology” Targeting abnormal lung fluid metabolism could reduce COVID-19 deaths and ventilator use.
53 citations
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September 2020 in “Stem Cell Research & Therapy” New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.
46 citations
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January 2020 in “Theranostics” Injecting a special gel with human protein particles can help hair grow.
41 citations
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December 2019 in “Stem Cell Reviews and Reports” Tooth regeneration could become possible by controlling how and when bioactive factors are released.
39 citations
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July 2021 in “Stem Cell Research & Therapy” Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.
35 citations
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August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
28 citations
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September 2020 in “Pharmaceutics” 3D-printed mesoporous scaffolds show promise for personalized drug delivery with controlled release.
18 citations
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July 2021 in “Molecular Medicine Reports” The WNT signaling pathway is crucial for mesenchymal stem cells' function and therapy success.
17 citations
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May 2023 in “Aesthetic Plastic Surgery” Stem cell therapies show the most promise for anti-aging benefits.
16 citations
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December 2018 in “ACS Biomaterials Science & Engineering” The new patch made of cell matrix and a polymer improves wound healing and supports blood vessel growth.
11 citations
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May 2023 in “Journal of Cancer Research and Clinical Oncology” CRISPR/Cas systems show promise for cancer treatment by targeting miRNAs, but delivery and specificity challenges remain.
11 citations
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January 2022 in “Theranostics” Wnt4 is essential for heart repair and could be a target for heart disease treatment.
11 citations
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May 2018 in “Philosophical Transactions of the Royal Society B” New materials help control stem cell growth and specialization for medical applications.
8 citations
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January 2022 in “Burns and trauma” Skin cell-derived vesicles can help heal skin injuries effectively.
8 citations
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November 2020 in “Nature Communications” Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
8 citations
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February 2020 in “Fertility and Sterility” Operative hysteroscopy is still the main treatment for Asherman syndrome, but more research is needed on post-surgery methods.
6 citations
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July 2023 in “Spine Surgery and Related Research” PRP shows promise for spinal pain but needs more guidelines before widespread use.
6 citations
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March 2021 in “Cytotechnology” Mesenchymal stem cells show promise in treating COVID-19 by reducing inflammation and aiding recovery, but more research is needed.
5 citations
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February 2024 in “Frontiers in bioengineering and biotechnology” Electrospun scaffolds can improve healing in diabetic wounds.
4 citations
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July 2025 in “International Journal of Nanomedicine” Nano-quercetin improves quercetin's effectiveness in treating diseases but faces challenges in safety and production.
4 citations
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January 2025 in “Frontiers in Pharmacology” Multiomics helps understand and improve skin healing and repair.
4 citations
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January 2022 in “Journal of clinical and translational research” Chitosan-based dressings reduce inflammation and speed up skin wound healing.