2 citations
,
March 2005 in “Journal of the American Academy of Dermatology” Equol may help with antiaging and skin health by boosting collagen and blocking certain hormones.
50 citations
,
November 2021 in “Viruses” Spironolactone may help reduce COVID-19 severity in men by blocking harmful effects of certain hormones.
46 citations
,
May 2021 in “Stem Cell Research & Therapy” Strontium ranelate helps cartilage growth by blocking a specific cell pathway.
40 citations
,
July 2015 in “Kidney International” IL-3 worsens lupus nephritis and blocking it improves kidney health.
23 citations
,
July 1993 in “Pharmacotherapy” Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
17 citations
,
January 2013 in “Talanta” A new method was developed to accurately measure enzyme activity related to prostate health.
15 citations
,
December 2018 in “International journal of environmental research and public health/International journal of environmental research and public health” EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.
13 citations
,
June 2017 in “Biochimie open” All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.
11 citations
,
July 2015 in “Frontiers in Cellular Neuroscience” Corticosterone makes ethanol more effective at blocking brain processes important for learning and memory.
6 citations
,
January 2015 in “Evidence-based Complementary and Alternative Medicine” Saw palmetto extract may help treat brain tumors by blocking a specific growth signal and blood vessel formation.
4 citations
,
August 2018 in “International Journal of Research -GRANTHAALAYAH” Catalase in processed meats may cause cancer by emitting electromagnetic fields.
February 2025 in “Chemico-Biological Interactions” 5-Fluorouracil causes hair loss by blocking signals needed for hair growth.
12 citations
,
November 2024 in “International Journal of Molecular Sciences” Hydroxytyrosol helps reduce liver injury by blocking certain inflammation pathways.
125 citations
,
January 1999 in “Drugs” Finasteride effectively treats baldness but may cause sexual side effects.
115 citations
,
January 2001 in “American journal of clinical dermatology” Eflornithine cream effectively reduces women's unwanted facial hair but hair returns if treatment stops.
101 citations
,
November 2019 in “The Plant Cell” AtZP1 protein stops root hair growth in plants by blocking certain genes.
74 citations
,
January 2014 in “Journal of Investigative Dermatology” High kallistatin levels in diabetics worsen wound healing by blocking important cell signals.
65 citations
,
August 2007 in “Experimental Dermatology” Human hair follicles can make and process prostaglandins, which may affect hair growth.
53 citations
,
November 2014 in “International Journal of Oncology” Wedelolactone may help prevent bone damage in breast cancer by blocking certain cell signals.
42 citations
,
May 2007 in “Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism” Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.
30 citations
,
December 2021 in “Frontiers in Microbiology” Cepharanthine effectively reduces Herpes Simplex Virus Type 1 by blocking certain cell pathways and promoting cell death.
30 citations
,
June 2010 in “Endocrine Related Cancer” SRD5A1 is crucial in advanced prostate cancer, and blocking both SRD5A1 and SRD5A2 is more effective than targeting SRD5A2 alone.
11 citations
,
August 2020 in “Diabetes” Testosterone helps human pancreatic cells increase insulin release.
8 citations
,
October 2020 in “Stem cell research & therapy” DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
7 citations
,
December 2022 in “Plants” Guava leaf extract may help treat hair loss and protect cells by blocking certain genes and fighting damaging molecules.
5 citations
,
December 2022 in “Viruses” Antiandrogens may help prevent or treat COVID-19 by blocking virus entry into cells.
February 2026 in “Toxicology Letters” MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.
April 2024 in “Applied biological chemistry” Piperine from black pepper can make hair less oily by blocking fat cell development in hair roots.
January 2023 in “Iranian Journal of Pharmaceutical Research” Stauntonia hexaphylla extract can help treat hair loss by blocking certain hormones.
56 citations
,
July 2014 in “PloS one” SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.