research Protein degradation: expanding the toolbox to restrain cancer drug resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
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180-210 / 1000+ results research Emerging Strategies in Smart Nano-PROTAC for Stimuli-Responsive Protein Degradation and Precision Cancer Therapy
Smart nano-PROTACs improve cancer treatment by targeting proteins more precisely and reducing side effects.
research Humic acids as drivers of plant growth: regulating root development and photobiology through redox modulation
Humic acids enhance plant growth by improving root development and photobiology.
research Anti-Aging, Anti-Inflammatory, and Cytoprotective Properties of Lactobacillus- and Kombucha-Fermented C. pepo L. Peel and Pulp Extracts with Prototype Skin Toner Development
Fermented pumpkin extracts can be effective for anti-aging and skin protection.
research Investigation of In Vitro and In Silico Anti-Inflammatory Potential of Carthamus caeruleus L. Root Juice
Carthamus caeruleus root juice may reduce inflammation.
research Recent Advances in Multiple Strategies for the Biosynthesis of Sesquiterpenols
Synthetic biology can improve sesquiterpenol production by using innovative microbial strategies.
research Protein S-Palmitoylation as Potential Therapeutic Target for Dermatoses
Targeting protein S-palmitoylation could lead to new skin disease treatments.
research Using proteomics to compare the molecular structures of sulfide and permeate-depilated sheepskins
The conclusion is that using bovine milk permeate to remove wool from sheepskins is eco-friendly and results in smoother, higher quality leather compared to traditional sulfide methods.
research Core-shell and core-amphiphilic branched shell nanocarriers based on biodegradable hyperbranched polymers, as potential drug delivery systems
The new biodegradable nanocarriers safely and effectively deliver drugs into the skin.
research Perilla frutescens: A Rich Source of Pharmacological Active Compounds
Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.
research Improving the treatment of bacterial infections caused by multidrug-resistant bacteria through drug repositioning
Using existing drugs for new purposes can effectively treat infections resistant to multiple antibiotics.
research Unraveling the mechanism of action of cepharanthine for the treatment of novel coronavirus pneumonia (COVID-19) from the perspectives of systematic pharmacology
Cepharanthine may help treat COVID-19 by targeting multiple pathways.
research Effect of Marine-Derived Saccharides on Human Skin Fibroblasts and Dermal Papilla Cells
Marine-derived saccharides may help reduce aging effects on skin and hair by promoting cell growth and collagen production.
research Synthesis and biological evaluation of esters of 16-formyl-17-methoxy-dehydroepiandrosterone derivatives as inhibitors of 5α-reductase type 2
Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.
research Urinary steroids in women with androgenic alopecia
Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.
research Steroid sulfatase inhibitors
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
research 5α-Reductase Inhibitors – The Finasteride Story
Finasteride safely treats enlarged prostate and male-pattern baldness.
research ATP-dependent chromatin remodeling during mammalian development
ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
research Nanozymes expanding the boundaries of biocatalysis
Nanozymes greatly improve biocatalysis by being stable, efficient, and versatile.
research Sulfatase inhibitors: a patent review
The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
research Phenotypic variation in biotinidase deficiency
Biotinidase deficiency has various symptoms and can be treated with biotin supplements.
research Minoxidil and the Treatment of Severe Hypertension
Minoxidil lowers blood pressure effectively but may cause unwanted hair growth and other side effects.
research The use of synthetic polypeptides in cosmetics
Synthetic polypeptides in cosmetics may help with anti-aging, but their effectiveness on real skin is uncertain.
research Is COVID-19 Gender-sensitive?
Men have more severe COVID-19 outcomes than women.
research Human genetic basis of coronavirus disease 2019
Genetic differences affect COVID-19 severity and treatment development.
research Knock-Down of Arabidopsis PLC5 Reduces Primary Root Growth and Secondary Root Formation While Overexpression Improves Drought Tolerance and Causes Stunted Root Hair Growth
Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.
research Teriflunomide in multiple sclerosis: an update
Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.
research Potential Medical Uses of Cannabigerol: A Brief Overview
CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.
research Human scalp hair: Modulation by various factors and hormones do estrogens inhibit or stimulate—A perplexing perspective
The effects of estrogen on human scalp hair growth are unclear and need more research.
research Amla Oil, a Pharmaceutical Product Based on Traditional Knowledge for Hair Loss Treatment
Amla oil may help treat hair loss.