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GlossaryEnzyme

An enzyme is a biological catalyst that accelerates chemical reactions in the body, including those involved in hair growth and maintenance. In the context of hair loss, certain enzymes can influence the metabolism of hormones like dihydrotestosterone (DHT), which is linked to androgenetic alopecia. Key distinguishing characteristics of enzymes include their specificity for substrates and their ability to function under physiological conditions, making them crucial for various biochemical pathways related to hair biology.

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research Impact of the Different Preparation Methods to Obtain Human Adipose-Derived Stromal Vascular Fraction Cells (AD-SVFs) and Human Adipose-Derived Mesenchymal Stem Cells (AD-MSCs): Enzymatic Digestion Versus Mechanical Centrifugation

124 citations , November 2019 in “International Journal of Molecular Sciences”

Standardized kits improve the quality and consistency of isolating stem cells from fat tissue.

research Enzymatic and non-enzymatic sulfation mechanisms in the biological actions of minoxidil

53 citations , January 1993 in “Biochemical Pharmacology”

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

research Chronic Pancreatitis and Persistent Steatorrhea: What Is the Correct Dose of Enzymes?

52 citations , March 2011 in “Clinical Gastroenterology and Hepatology”

Enzyme doses for chronic pancreatitis should match meal size, not patient size.

research Glucose‐Activated Programmed Hydrogel with Self‐Switchable Enzyme‐Like Activity for Infected Diabetic Wound Self‐Adaptive Treatment

48 citations , February 2025 in “Advanced Materials”

The hydrogel speeds up diabetic wound healing by adapting to glucose levels and releasing insulin.

research BIOCHEMICAL ANALYSIS OF HAIR GROWTH FROM THE ASPECTS OF AGING AND ENZYME ACTIVITIES

46 citations , February 1983 in “The Journal of Dermatology”

Hair regrowth slows with age due to changes in enzyme activity.

research Local and Systemic Reduction by Topical Finasteride or Flutamide of Hamster Flank Organ Size and Enzyme Activity

37 citations , November 1995 in “Journal of Investigative Dermatology”

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

research Enzyme Treatment of Wool and Specialty Hair Fibers

35 citations , February 2006 in “Textile Research Journal”

Enzymes xylanase and pectinase clean wool and specialty hair fibers effectively without damage, offering an eco-friendly alternative to soap and hot water.

research Enzymology of the hair follicle.

31 citations , August 2001 in “PubMed”

Hair follicles convert androgens, affecting hair loss patterns.

research Enzyme Replacement Therapy Ameliorates Multiple Symptoms of Murine Homocystinuria

29 citations , December 2017 in “Molecular therapy”

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

research Enzyme Typing of Human Hair Roots

27 citations , April 1978 in “Journal of Forensic Sciences”

Enzyme typing can reliably characterize human hair.

research Novel enzymatic assay predicts minoxidil response in the treatment of androgenetic alopecia

27 citations , November 2013 in “Dermatologic Therapy”

New test predicts if hair loss treatment will work.

Enzyme-Triggered On-Demand Release of a H2O2-Self-Supplying CuO2@Fe3O4 Nanoagent for Enhanced Chemodynamic Antimicrobial Therapy and Wound Healing

research Enzyme-triggered on-demand release of a H₂O₂-self-supplying CuO₂@Fe₃O₄ nanoagent for enhanced chemodyamic antimicrobial therapy and wound healing

17 citations , January 2024 in “Journal of Materials Chemistry B”

A new nanoagent effectively kills bacteria and speeds up wound healing.

research Polymorphic Enzyme Systems in Human Hair Sheath Cells

11 citations , April 1982 in “Journal of the Forensic Science Society”

Enzyme presence in hair sheath cells decreases over time, affecting forensic analysis.

research Enzymatic phosphorylation of hair keratin enhances fast adsorption of cationic moieties

11 citations , January 2016 in “International Journal of Biological Macromolecules”

Enzymatic phosphorylation of hair keratin improves the effectiveness of hair products with cationic ingredients.

research Enzyme-linked immunosorbent assays for doping control of 5α-reductase inhibitors finasteride and dutasteride

10 citations , May 2010 in “Analytica Chimica Acta”

New tests detect finasteride and dutasteride in urine quickly and easily.

research A Simple Method to Extract DNA from Hair Shafts Using Enzymatic Laundry Powder

8 citations , July 2013 in “PLoS ONE”

DNA can be quickly and effectively extracted from hair using laundry powder.

research Isolating Dermal Papilla Cells from Human Hair Follicles Using Microdissection and Enzyme Digestion

6 citations , January 2020 in “Methods in molecular biology”

The method successfully isolates cells that are important for hair growth and could help study hair loss.

research Phenolic composition, enzyme inhibitory, and antioxidant activity of Bituminaria bituminosa

6 citations , October 2016 in “Food Science and Biotechnology”

The water extract of Bituminaria bituminosa, high in phenolic compounds, shows strong antioxidant and enzyme inhibitory potential.

research Role of skin enzymes in metabolism of topical drugs

6 citations , September 2024 in “Metabolism and Target Organ Damage”

Skin enzymes convert topical drugs into active forms, affecting drug effectiveness and safety.

Preparation of a Highly Specific Single Chain Variable Fragment Antibody Targeting Miroestrol and Its Application in Quality Control of Pueraria Candollei by Enzyme-Linked Immunosorbent Assay

research Preparation of a highly specific single chain variable fragment antibody targeting miroestrol and its application in quality control of Pueraria candollei by enzyme‐linked immunosorbent assay

5 citations , April 2019 in “Phytochemical Analysis”

The new ELISA method is reliable and eco-friendly for checking the quality of Pueraria candollei.

research The effect of proteolytic enzymes on hair follicles of transgenic mice expressing the lac Z‐protein in cells of the bulge region

5 citations , July 1999 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Proteolytic enzymes damage hair follicles by detaching stem cells.

research Enzymatic Method for Assessing Hair Damage with Reduction and Subsequent Oxidation

4 citations , January 2007 in “Sen'i Gakkaishi”

Permed hair degrades faster and shows more damage after protease treatment compared to untreated hair.

research Enzyme Inhibitors from Gorgonians and Soft Corals

4 citations , January 2023 in “Marine Drugs”

Marine compounds from gorgonians and soft corals show promise for drug development, especially for chronic disorders.

research Effects of combined use of keratinolytic enzymes and sugarcane fibre on the hairball excretion in cats

3 citations , August 2019 in “Journal of Animal Physiology and Animal Nutrition”

Combining sugarcane fiber and enzymes reduces hairballs in cats.

research A Sensitive Assay for the Enzyme Activity in Hair Follicles and Epidermis that Catalyses the Peptidyl-Arginine-Citrulline Post-translational Modification

3 citations , April 2015 in “Current problems in dermatology”

A more sensitive assay was developed to detect enzyme activity converting arginine to citrulline in hair follicles.

research Application of an Enzymatic Method for Identifying Hair Treatments

3 citations , January 2007 in “Journal of health science”

The enzymatic method can effectively identify chemical treatments on hair.

research Improvement in Scalp Hair in Middle Aged Women Using Oral Enzyme Food and Collagen

2 citations , January 2015 in “Jounal of The Korean Society of cosmetology”

Taking enzyme food and collagen together improves scalp hair health in middle-aged women more than taking them separately.

research The effect of proteolytic enzymes on hair follicles of transgenic mice expressing the lac Z-protein in cells of the bulge region

2 citations , July 1999 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Proteolytic enzymes damaged hair follicle stem cells in transgenic mice.

research SULT1A1 (Minoxidil Sulfotransferase) enzyme booster significantly improves response to topical minoxidil for hair regrowth

1 citations , June 2021 in “Journal of Cosmetic Dermatology”

Enzyme booster SULT1A1 greatly enhances hair regrowth with minoxidil.

research Effects of Lavender Oil on Hair Growth-Relevant Enzyme Activity and Cytokine Expression in C57BL/6 Mice

1 citations , March 2016 in “Journal of Investigative Cosmetology”

Lavender oil promotes hair growth in mice.