research Clinicopathological features and expression of four keratins (K10, K14, K17 and K19) in six cases of eruptive vellus hair cysts
Eruptive vellus hair cysts likely originate from the infrainfundibulum and sebaceous duct.
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630-660 / 1000+ resultsresearch Epidermal and hair follicle trans glutaminases and crosslinking in skin
research Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation
mTORC2 is crucial for healthy skin barrier by regulating lipids and filaggrin.
research Netherton's syndrome and ichthyosis linearis circumflexa.
Netherton's syndrome may have a familial link and doesn't always include atopy.
research Expression of EGF,IGF-Iand IGF-IR Gene in Mink's Skin and Hair Follicles of Pelting Period
EGF, IGF-I, and IGF-IR genes are crucial for mink skin and hair growth.
research Dermal EZH2 simultaneously orchestrates dermal differentiation and epidermal proliferation during murine skin development
Dermal EZH2 controls skin cell growth and differentiation in mice.
research Hoxc13 and homologs of mammalian hair keratins are required for the cornification of nuptial pads in Xenopus frogs
The study investigates the role of Hoxc13 and type II hair keratin homolog krt59 in the cornification of nuptial pads in Xenopus frogs. It reveals that the expression of Hoxc13 is enriched in the skin of the forelimbs, and its inactivation via CRISPR-Cas9 leads to the loss of krt59 expression and epithelial cornification in nuptial pads. This suggests that cornified nuptial spines have evolved similarly to mammalian hair by adapting the ancestral cornification program of skin appendages. The findings highlight the evolutionary parallel between the development of these structures in frogs and hair in mammals.
research Arachidonate 12-Lipoxygenase Inhibitors Promote S100A3 Citrullination in Cultured SW480 Cells and Isolated Hair Follicles
Inhibiting ALOX12 can help hair cuticle maturation by increasing S100A3 citrullination.
research FOXN1 Is Critical for Onycholemmal Terminal Differentiation in Nude (Foxn1nu) Mice
The Foxn1 gene is essential for normal nail and hair development.
research Human hair keratins
research Evidence for murine cutaneous immune surveillance localized to hair follicle epithelium
Hair follicles in mice help detect and respond to germs.
research 8280186 Biomarkers for Occupational Hand Eczema: Improving Diagnostic Differentiation
Certain biomarkers can help distinguish between irritant and allergic contact dermatitis.
research SnapshotDx Quiz: February 2018
Blocking certain pathways with kinase inhibitors may help treat cutaneous lupus erythematosus.
research A Scandinavian case of skin fragility, alopecia and cardiomyopathy caused byDSPmutations
A child with skin and heart issues had rare genetic mutations affecting skin and heart cell cohesion.
research 269 Down-regulatory role of cholecystokinin on psoriatic epidermal inflammation
Cholecystokinin may help reduce skin inflammation in psoriasis.
research Molecular characterization of xerosis cutis: A systematic review
It's unclear which molecules best characterize dry skin due to inconsistent findings.
research Epidermolysis Bullosa in Calves in the United Kingdom
Epidermolysis bullosa in calves was not caused by mutations in the keratin genes bKRT5 and bKRT14.
research Soluble and insoluble collagen and elastin in the rat hair cycle
research Harlequin ichthyosis (ichq): a juvenile lethal mouse mutation with ichthyosiform dermatitis.
The harlequin ichthyosis mouse mutation causes thick skin and early death, resembling a human skin disorder.
research Morphea‐like lesion following topical endectocide application in a cat
A cat developed a skin lesion from a topical solution, which healed with minoxidil treatment.
research Epidermis reconstructed from the outer root sheath of human hair follicle on de-epidermized dermis. Effect of retinoic acid
research Expression of Uncoupling Proteins in Human Skin and Skin-Derived Cells
research Characteristic intraepidermal nerve fibre endings of the intervibrissal fur in the mystacial pad of the rat: morphological details revealed by intravital methylene blue staining and the zinc iodide-osmium tetroxide technique
Methylene blue staining effectively highlights detailed nerve structures in rat fur.
research Keratin expression in the normal nail unit: markers of regional differentiation
Different parts of the nail express different keratins, showing unique patterns of differentiation.
research Diagnosis and therapeutic management of psoroptic mange in large white Yorkshire piglets: A case report
The piglets fully recovered from psoroptic mange after treatment.
research Extensive alopecia areata: A multicenter review of 132 patients
The study found that severe alopecia areata affects any age, treatments often give temporary results, and some factors predict worse outcomes.
research Recent advances in congenital ichthyoses
New genes linked to ichthyosis were found, but there's still no cure; treatment options are improving.
research Disorders of Keratinization
The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.
research Skin barrier, phenotypic and genotypic characterisation of autosomal recessive ichthyosis in TGM1 ‐deficient Jack Russell Terriers and response to topical ceramide
Topical ceramide treatment partially improves the skin condition in Jack Russell Terriers with a genetic skin disorder.
research Hypotrichosis in a child with olmsted syndrome
A child with Olmsted syndrome showed mild improvement in hair and skin issues with treatment.