32 citations
,
October 2015 in “Frontiers in Cellular Neuroscience” DHT is needed for long-term depression, while E2 is needed for full long-term potentiation in male rat brains.
CaBP1 and CaBP2 are important for continuous hearing by preventing inactivation of calcium currents in ear cells, with CaBP2 also able to restore hearing when reintroduced.
3 citations
,
August 2021 in “Nutrition research” Estrogen affects how vitamin A is processed in mouse skin, which may impact acne treatment, hair growth, and skin defense.
November 2022 in “Journal of Investigative Dermatology” Neutrophils quickly respond to skin injury.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
July 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” FAKΔe4 helps cells sense and respond to different stiffness levels in their environment.
227 citations
,
January 1998 in “Journal of biological chemistry/The Journal of biological chemistry” Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.
6 citations
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October 2022 in “Frontiers in Physiology” Calcium channels are vital for normal skin function and their dysfunction can lead to skin issues.
24 citations
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November 2019 in “Experimental Dermatology” PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
20 citations
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December 2013 in “PLoS ONE” β1 integrin is essential for the survival, growth, and movement of human epithelial progenitor cells.
1 citations
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March 2024 in “Genes & Diseases” EBF1 controls hair type and length.
30 citations
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June 1993 in “The Journal of Cell Biology” The oncoprotein causes abnormal hair growth without increasing skin cancer risk.
Muscarinic acetylcholine receptors help regulate and promote hair growth.
August 2016 in “Journal of Investigative Dermatology” Activating Nrf2 can improve wound healing by increasing hair follicle stem cells.
December 2021 in “Figshare” BBS7 is crucial for maintaining healthy gums by regulating important signaling pathways.
13 citations
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July 1994 in “PubMed” Keratins K6 and K16 are expressed more freely in regenerating mouse skin than K1 and K10.
May 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Prostaglandin D2, found in higher levels in bald scalps, stops hair growth, suggesting that blocking its receptor could potentially treat hair loss.
January 2020 in “Nihon Yakuri Gakkai nenkai yoshishu” Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.
UBC13 and UBC22 enzymes are important for plant growth and development in Arabidopsis thaliana.
18 citations
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July 2006 in “British Journal of Dermatology” Connexin 30 is usually absent in normal skin but can appear in certain skin conditions.
January 2007 in “日本看護学会抄録集 成人看護1” Certain amino acids in 5AR1 and 5AR2 are crucial for binding and resistance to Finasteride.
24 citations
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December 2018 in “Life sciences” Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
5 citations
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February 2023 in “Frontiers in Veterinary Science” Ovine dermal papilla cells are promising for hair growth research due to their stable properties and hair-inducing abilities.
July 2005 in “TSpace (University of Toronto)” Ghrelin and its receptors likely aren't risk factors for PCOS.
2 citations
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October 2025 in “Antimicrobial Agents and Chemotherapy” Cepharanthine can block enterovirus entry and protect against infection.
2 citations
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October 2023 in “Philosophical Transactions of the Royal Society B Biological Sciences” Different PADI isoforms help cells develop diverse functions.
13 citations
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September 2012 in “Cell & tissue research/Cell and tissue research” pCLCA2 protein may help maintain skin structure and function.
17 citations
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August 2012 in “Journal of Medical Genetics” A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.
15 citations
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October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Erlotinib causes skin inflammation through IL-1, which can be reduced by anakinra.
February 2016 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” A new TP63 mutation was found in a baby with EEC syndrome, showing the need for TREC testing to check for immune issues.